External Email - Use Caution Thank you Stefano!
Just an additional curiosity, is there any function within Freesurfer that you think could be used to map and quantify microbleeds in SWI data? Thanks for the help, Arianna Il giorno mer 14 mag 2025 alle ore 17:26 Stefano Cerri <ste.45....@gmail.com> ha scritto: > External Email - Use Caution > > Hi Arianna, > > 1) Yes. Please note that the method was tuned and mostly tested on MS > patients. > > 2) These two versions of SAMSEG model WMH/ WM lesions differently and > cannot be directly compared. The basic SAMSEG is not designed for accurate > WMH or WM lesion estimation. Note that you can use the lesion version of > SAMSEG on scans without lesions (see Fig. 6 here > <https://secure-web.cisco.com/1KM7GJ1i4uKDVvBOOHjfxLxbNpEbDV37ju32_ri0-iGtre9ZQKasYmqnwK6bi5vzt5-BaRS02ywgcOcI--IezHyHTAKt807vpLrXUZvO33iKmYOL0EeUkqkVhKXj38poEFY9bY4Djm69SgNrHqC2TpJRpU5OQUybXs5s7nPnXPv0ArkvG_YpXaiip_cs58dLk8TygUTgVuRtW8x9gYHo_BSTpTQs6pwsWwQ2nel-ejGeDe1nkcKTJcqBaT8vZrbLqyVpzVwZRXQDIXUhOjCyNPkbtTJdnT8BSGUjOyXcMp0Etejbfjh9bThJhaEK0tzEhXSLDLIgxCcSmrxk53keXlg/https%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Farticle%2Fpii%2FS1053811920309563> > ). > > 3) Yes. Note that SWI data might not add valuable information to the > lesion and whole-brain segmentation task. My suggestion is to visually > inspect a couple of subjects with and without SWI data. > > Stefano > > Sent on behalf of Arianna Menardi: > > ---- > > Dear Experts, > > I'm trying to quantify the volume of some white matter lesions in an > elderly group. I have tried using both Samseg cross-sectional, as well as > Samseg for MS lesions. > > I am new to the approach so I have 3 main questions: > 1. Can I use Samseg for MS lesions even if my patients present WM lesions > but are not MS patients? > 2. the estimated values of WM-hypointensities derived from the basic > version of Samseg are almost half in size compared to the output 'Lesions" > of Samseg specific for MS lesions. What is hence the difference between the > two approaches that could explain such a big difference in the output? > 3. Can I use Samseg combining T1w, FLAIR and SWI data? Or the algorithms > are not suited for SWI images? > > Thank you for your help, > Arianna > > The information in this e-mail is intended only for the person to whom it > is addressed. 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