Sent on behalf of Arianna Menardi:

----

Dear Experts,

I'm trying to quantify the volume of some white matter lesions in an elderly 
group. I have tried using both Samseg cross-sectional, as well as Samseg for MS 
lesions.

I am new to the approach so I have 3 main questions:
1. Can I use Samseg for MS lesions even if my patients present WM lesions but 
are not MS patients?
2. the estimated values of WM-hypointensities derived from the basic version of 
Samseg are almost half in size compared to the output 'Lesions" of Samseg 
specific for MS lesions. What is hence the difference between the two 
approaches that could explain such a big difference in the output?
3. Can I use Samseg combining T1w, FLAIR and SWI data? Or the algorithms are 
not suited for SWI images?

Thank you for your help,
Arianna

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