External Email - Use Caution        

The error occurred just immediately after having loaded the surfaces in
freeview. There have been no modifications as the output is the one that is
given straight out of recon-all command. The issue is encountered both in
freesurfer 7.2.0 and 7.4.1 versions.

For what concern the wm edits, I performed some volume edits hoping to fix
the hypo- and hyper-intensity problems, but it is more of a side question
with respect to the main problem, that is the misregistration of the
surfaces.

As for the offset, I mean that the surfaces are not overlapping the volume
images, not the orig.mgz nor the wm.mgz ones, giving me the feeling that
there is a misregistration problem.
I tried to treat it as a tailarach.xfm error, so after following the
tutorial I performed the command
tkregisterfv --s ./subj01 --fstal
Though the recon-all launched after this did not produce anything different
from the beginning.

I tried the command
mri_convert --conform ./subj01/mri/orig.mgz orig_fixed.mgz
And it gives me as output the message:

input_transform(): error reading transform elem [1,1]
input_transform: error reading transform
error: error loading transform from <path_to_file>/talairach.xfm

The xform info prints out this matrix:
x_r = -1.0000  y_r = 0.0000  z_r = 0.0000  c_r = 0.9241
x_a = 0.0000 y_a = 0.0000 z_a = 1.0000 c_a = -5.7364
x_s = 0.0000  y_s = -1.0000  z_s = -0.0000  c_s = -19.9210

If you need anything else please reach me out.
I am available also to schedule a brief call to find out what's going on,
as this issue is what keeps me apart from being able to use the brain model
for an important project.

Thank you in advance,
Tommaso Mariani

Il Lun 17 Mar 2025, 14:56 Douglas N. Greve <dgr...@mgh.harvard.edu> ha
scritto:

> Did that error happen before you did anything to the volume? Can you give
> a list of commands you used to get to that point? What do you mean by
> offset?
>
> On 3/10/2025 4:23 AM, Tommaso Mariani wrote:
>
>         External Email - Use Caution
> Hi everyone,
> I am experiencing a tricky situation in freesurfer. Due to hypo- and
> hyper-intensity problems I obtained a bad reconstruction and I've been
> working on it since. My first question is then: do I need to refresh the
> aseg file after the wm.mgz intensities modifications?
>
> However I also noticed that when I loaded the surface to verify the
> corrections they were all with a significant offset and this message was
> printed on the console:
> Warning: MatrixInverse failed.
> Did not find any volume info
> Warning: MatrixInverse failed.
> Did not find any volume info
> Warning: MatrixInverse failed.
> Did not find any volume info
> Warning: MatrixInverse failed.
> Did not find any volume info
>
> Together with that, I was also unable to obtain the final parcellization,
> possibly due to the absence of correlation between the volumes and surfaces.
> I already tried to manually adjust the offset and relaunch the
> reconstruction, as suggested in the Freesurfer documentation for tailarach
> errors, but it looks like it did nothing to it.
>
> If you need any file or info to examine the situation further, feel free
> to contact me, I would really appreciate your help.
> Thanks in advance,
> Tommaso Mariani
>
>
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