On 1/28/2025 12:51 PM, Andrade Rey René wrote:

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Dear community,

I have tried the tutorial for PETsurfer. I would like to ask some questions.

1) I have seen in the tutorial when you do PVC correction it is done on PET dynamic raw data. Is this correct? Because I have seen some tutorial where it is suggested on the motion corrected by AFNI image so called pet.mc.nii.gz
If you are going to do motion correction, then you should do that before PVC.

2) I also would like to compute hypometabolism on epileptic patients based on a dynamic PET so called Patlak Kinetic modeling. Is that possible with Freesurfer? I know there is Qmodeling toolbox in SPM but I cannot get access to their toolbox (some issue about the download)  and I don’t know if there is another workaround.
I don't have patlak implemented in FS; I'll add it to the list.

If not possible to do Patlak with FreeSurfer is it correct to assume the mean of the dynamic PET will provide epileptogenic zone for epileptic patients based on FDG-PET as hypo metabolic regions?
I don't know

Sincerely,
Rene Andrade.

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