The glm can be run on this data in theory. With only 5 time points, you probably won't have much power though. What are you trying to test?

On 2/1/2025 11:56 PM, Isabella Rossellini wrote:

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Hello Freesurfer users/experts,

I am working with Freesurfer 7.4.1 on a MacStudio (macOS 15.2) and I would like to ask your opinion about the following.

Basically, we had an anxiety treatment study and I would like to analyze one subject who has 5-time points (0, 3, 6, 9, 12) with a longitudinal pipeline, two-stage model. Is it possible to run this on one person only and see the changes between these time points?

I have never done this before on one subject so I am not sure what the best approach would be to look at the changes. After running the longitudinal preprocessing (base, long), should I generate the tables of freesurfer parcellation/segmentation stats data
(aparcstats2table, asegstats2table)?
Or can I just follow the two stage model steps? Maybe glm only works on a group of subjects. *MailScanner has detected a possible fraud attempt from "secure-web.cisco.com" claiming to be* https://surfer.nmr.mgh.harvard.edu/fswiki/LongitudinalTwoStageModel <https://secure-web.cisco.com/1iC7gpXrtEAUPrcmI22C302poe7thUhcUmsjgK95UydNOqu3VNOqyHRmhU4DzBRXfeRcCEznWAF1ghpJZhaGCFK_zU17DxJor1VizKN_05K6Tpo8SOcCBr7Fp4tG_ZY7-Unx9Q11f00p0Krish0KpQWPAk1Qp9wQhAwo4vc4biMn1MeR_f_16rPJka3Yem_EVmYLnOd_MoBIFSmWUWYmtLz7Hzhn6YQe263ih4gPbLM491KKg6up62zvW_82b7YAiy5OlBqr1A6fQ4a1RkcIhY3ZryUCPX7DZ0KaqPEie0uRPXXZwcwKGpVWS6C681WDl_7vgcqJasq-CUutO64aT7w/https%3A%2F%2Fsurfer.nmr.mgh.harvard.edu%2Ffswiki%2FLongitudinalTwoStageModel>

(We have 9 more subjects - 10 in total - so I was hoping to visualize the pattern of changes one by one, in each subject, since these patients showed different changes in anxiety based on self-reported
questionnaires)

Sincerely,
Isa Rosselini


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