FemaleNP only has two members but you are trying to fit 3 parameters (offset, AgeM slope, meanthickness slope). You need to have at least 3 members to do this, and you'll probably want much more.
On 10/21/2024 2:37 PM, Chen Yang wrote: > External Email - Use Caution > > Dear FreeSurfer experts, > > I tried to examine the thickness differences between two groups after > controlling for the age, gender, and mean thickness, while I got an error > message below: > > ERROR: matrix is ill-conditioned or badly scaled, condno = 1e+08 > Possible problem with experimental design: > Check for duplicate entries and/or lack of range of > continuous variables within a class. > If you seek help with this problem, make sure to send: > > Your command line: mri_glmfit.bin --y > glm/FB_demo_lh_CT/lh.FB_demo_lh_CT.thickness.10B.mgh --fsgd > glm/FSGD_files/createFSGD/FB_demo_lh_CT/FB_demo_lh_CT.fsgd --C > glm/FB_demo_lh_CT/PS-NP.mtx --C glm/FB_demo_lh_CT/NP-PS.mtx --surf 43kids lh > --glmdir glm/FB_demo_lh_CT/lh.FB_demo_lh_CT.thickness.10B.glmdir > The FSGD file (if using one) > And the design matrix above > Attempting to diagnose further > SumSq: Min=1.258825 (col 10), Max=5.384785 (col 5) > ... could not determine the cause of the problem > > > I have searched this problem in the mail archive. I have done the > normalization for all covariables (age and mean thickness). Sex and test > condition are treated as class variables. So I have no idea about the cause > of the error. Here I attached the FSGD file and the matrix. The contrast is > 0.5, -0.5, 0.5, -0.5, 0,0,0,0,0,0,0,0. Can someone help me? Thank you! > > > Best regards, > Chen > > > > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Mass General Brigham Compliance HelpLine at https://www.massgeneralbrigham.org/complianceline <https://www.massgeneralbrigham.org/complianceline> . Please note that this e-mail is not secure (encrypted). If you do not wish to continue communication over unencrypted e-mail, please notify the sender of this message immediately. Continuing to send or respond to e-mail after receiving this message means you understand and accept this risk and wish to continue to communicate over unencrypted e-mail.
