External Email - Use Caution Dear FreeSurfer experts,
I tried to examine the thickness differences between two groups after controlling for the age, gender, and mean thickness, while I got an error message below: ERROR: matrix is ill-conditioned or badly scaled, condno = 1e+08 Possible problem with experimental design: Check for duplicate entries and/or lack of range of continuous variables within a class. If you seek help with this problem, make sure to send: Your command line: mri_glmfit.bin --y glm/FB_demo_lh_CT/lh.FB_demo_lh_CT.thickness.10B.mgh --fsgd glm/FSGD_files/createFSGD/FB_demo_lh_CT/FB_demo_lh_CT.fsgd --C glm/FB_demo_lh_CT/PS-NP.mtx --C glm/FB_demo_lh_CT/NP-PS.mtx --surf 43kids lh --glmdir glm/FB_demo_lh_CT/lh.FB_demo_lh_CT.thickness.10B.glmdir The FSGD file (if using one) And the design matrix above Attempting to diagnose further SumSq: Min=1.258825 (col 10), Max=5.384785 (col 5) ... could not determine the cause of the problem I have searched this problem in the mail archive. I have done the normalization for all covariables (age and mean thickness). Sex and test condition are treated as class variables. So I have no idea about the cause of the error. Here I attached the FSGD file and the matrix. The contrast is 0.5, -0.5, 0.5, -0.5, 0,0,0,0,0,0,0,0. Can someone help me? Thank you! Best regards, Chen -- Chen Yang PhD Student Independent Research Group 'Milestones of Early Childhood Development' Max Planck Institute for Human Cognitive and Brain Sciences Email:ya...@cbs.mpg.de
GroupDescriptorFile 1 Title FB_demo_lh_CT Class FemalePS Class FemaleNP Class MalePS Class MaleNP Variables AgeM meanthickness Input PA3K FemalePS 1.513793103 1.411875 Input TK1K FemalePS 1.168965517 0.1353125 Input NA5K FemalePS 1.168965517 -0.6753125 Input KV3K MalePS 1.398850575 -2.279375 Input KN8K FemalePS 0.594252874 0.632083333 Input SLQK MalePS 0.93908046 -2.535729167 Input HF5K FemalePS 0.594252874 0.394375 Input SMHK MalePS 0.594252874 -1.763229167 Input HW2K MaleNP 1.743678161 -0.580729167 Input LA2K FemalePS -1.244827586 0.492395833 Input SK4K FemalePS -0.325287356 0.105729167 Input LM3K FemalePS 0.479310345 -0.491458333 Input WM6K MalePS -1.244827586 -1.556979167 Input KA6K FemalePS -0.325287356 -0.41375 Input GM6K FemalePS -1.014942529 1.24 Input LT6K MaleNP 0.709195402 -0.035416667 Input HLHK MalePS -1.244827586 1.867708333 Input GP5K FemalePS -1.129885057 0.236458333 Input BT4K FemalePS -1.589655172 -0.028854167 Input BJEK MalePS -0.095402299 -1.095833333 Input KC6K FemalePS 0.01954023 0.43625 Input BLAK MaleNP -0.210344828 -1.8484375 Input TE1K MalePS -0.095402299 0.044270833 Input HABK FemalePS 0.134482759 1.6196875 Input OI1K FemalePS -0.095402299 -0.248645833 Input KN9K FemalePS -0.9 0.38375 Input RA6K FemalePS 0.249425287 -0.010104167 Input KT5K FemaleNP -1.359770115 0.558125 Input GLAK MalePS 0.364367816 1.043229167 Input NC1K FemalePS -1.129885057 1.6225 Input VC2K FemalePS 0.01954023 0.531770833 Input TG2K MalePS 0.249425287 -1.179375 Input PLAK FemalePS 1.054022989 -0.992708333 Input PA4K MalePS 1.054022989 -0.615 Input MI2K FemalePS 1.398850575 0.713020833 Input SH8K FemalePS -0.555172414 0.406354167 Input TW1K FemalePS 1.513793103 0.488229167 Input VE2K FemalePS 1.513793103 -0.5734375 Input HMHK FemaleNP 1.283908046 1.128333333 Input LJAK MaleNP -0.9 0.456875 Input AN1K MalePS -0.9 0.030208333 Input KJBK MaleNP -0.555172414 0.1825 Input WK4K FemalePS -0.9 -0.1815625 Input WF5K MalePS -0.440229885 -0.209479167 Input SB7K MalePS -0.440229885 0.4803125 Input LS5K FemalePS -0.9 -0.450416667 Input MF6K FemalePS -2.164367816 1.144375
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