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Dear Freesurfer Experts,

I’m evaluating WMH-SynthSeg for white matter lesion segmentation using the most 
recent development version, and ran into similar issues reported last month: 
https://secure-web.cisco.com/15YjRoSDCoF2Q2A8SbHg4Jal044A5FQlCGhkswUXxVl-RCU42MnhOnROjNeQ0N8aY1j5q-c0EIZxuvWi9b2BY3_RcavrvdsqyUMxh0pJBCvdkvBk9heTacObFxDABUoLfQoYBCuo8MRJ1klcb2u-ZgeCAQZTNFG_VGq2v37dfIRoJlZvFB1c7q3NxokKuuopV7jXHQBzMClEUl8L-3SbglD9DmdXGhFbM9SoKFLSNoyBtgr7QewklOtqD6BFOeQLd1Yxc5SC-8_y9q_bmcb-bfcd6vKxUshHlcYcK1lJRasJnuos-8ajTKLn85B1QuYJvSGfzPXXsqLcOepc8n_u7ZA/https%3A%2F%2Fwww.mail-archive.com%2Ffreesurfer%40nmr.mgh.harvard.edu%2Fmsg76177.html

I was running this as CPU only on a Mac Studio (M2 Ultra) with 192GB RAM. I 
tried is multiple times with 1-8 threads, and the process was killed in each 
instance. Viewing memory usage through the Mac OS Activity Monitor while 
running WMH-Synthseg, it appears that memory usage ramps up to >200GB (at which 
time the process is killed). With system resources consuming ~10GB RAM, it 
seems there should still be sufficient memory if it only requires ~32GB RAM. 
Are there any other (i.e., non-documented) options for running the process on 
CPU only? Any other suggestions are greatly appreciated.

Regardless of specific suggestions you may have, I wanted to bring this to your 
attention as a potential bug that could produce memory leaks or similar issues.

Thanks,
Drew


Andrew R. Bender, Ph.D.  |   Staff Neuroimaging Research
Cleveland Clinic Lou Ruvo Center for Brain Health


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