External Email - Use Caution Hi FS experts,
I was wondering if someone could help me get the following issue resolved. Thanks. ---------- Forwarded message --------- From: Martin Juneja <mj70...@gmail.com> Date: Fri, Dec 8, 2023 at 11:03 AM Subject: Case-controls study ! To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu> Hello FreeSurfer experts, In my case-control study, I have a dataset of 5 healthy controls (HCs) and one patient (PAT). I was wondering if there is any way to perform GLM for PAT > HCs on brain morphometry data. When I tried to follow instructions from here: https://secure-web.cisco.com/1aK-KNfU8HH_e-fpaIAGAkK_0d2hcDIl4JpjyDUomASQEQQJehjuhA0YYNd1-yCMyLrNtRVInHC0sL4ZGQSm_hx-e7WqN75sm22gAExeDyUksUiv3NFy2UeyAzhzh7cNHQd3Uf5EAsh0E1za-xLWZQArzwTi3Bn_5I9N1UoxsMjYkGv5oZxPiqEXVD5BEsxQiOPkQtZJuTIDOtckipDfTK-LEDpsCXFCAShvieYfbxxg0ec00jOhHeoAyF4ZLaU_-CqhBmbOtWCJUC56qpOxRmizvYekBnUs8Nlzv3M50Fu7V8kklIdu8eSaJSTnIRHLld9QqWlnqRDFQoChfS_1bcQ/https%3A%2F%2Fsurfer.nmr.mgh.harvard.edu%2Ffswiki%2FFsTutorial%2FGroupAnalysis, the mri_glm fit command gives me the following error: Class Size and Means of each Continuous Variable 1 HC 5 24.2000 0.6000 2 Tumor 1 50.0000 1.0000 ERROR: Class Tumor has 1 members. With 2 variables and using DODS, you need at least 3 members It seems at-least three subjects are required in the Tumor category - because I have age and sex covariates in my fsgd file. I was wondering if there is any way to still perform the above GLM analysis or any other alternatives available to compare HCs vs one PAT. Thanks!
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