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Hello FreeSurfer experts,

In my case-control study, I have a dataset of 5 healthy controls (HCs) and
one patient (PAT). I was wondering if there is any way to perform GLM for
PAT > HCs on brain morphometry data.

When I tried to follow instructions from here:
https://secure-web.cisco.com/1og9s8_rd4Lyx1NIwR7d0GRha020qNYi0MbIToxO7mZZ68u0-1Mqs2-nbpGVMe8z4QqGla-8tTv7UImDK5tHBH8VpWK0lmJo4NejFJBd1Lo4QLqd8RIC_S2rJZEoTQuLgZ85yECAm8PcZ5AgEXxuwBNvU1NpEpny1iM26ExZEKUZeYJA5POwSpMNbFCDiNaG3yKTTOz69SZ6JlqCG9LNRz1oqhI9QpjRhtIsh043XuY5Pa8hnoe9MElhlpjE0zHCFgO8Jx90FD5Apzz6F5alIZRoxUR2qV-qRvGz39xFjyHsv2mJZ-9ZRjsssKMs-b8zAPBM7qebGdnxa1mxGiJ00_w/https%3A%2F%2Fsurfer.nmr.mgh.harvard.edu%2Ffswiki%2FFsTutorial%2FGroupAnalysis,
 the
mri_glm fit command gives me the following error:

Class Size and Means of each Continuous Variable

1 HC  5  24.2000   0.6000

2 Tumor  1  50.0000   1.0000

ERROR: Class Tumor has 1 members. With 2 variables and using DODS, you need
at least 3 members


It seems at-least three subjects are required in the Tumor category -
because I have age and sex covariates in my fsgd file.


I was wondering if there is any way to still perform the above GLM analysis
or any other alternatives available to compare HCs vs one PAT.


Thanks!
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