External Email - Use Caution Dear Prof Greeve,
Gentle reminder for this question, Many thanks Best wishes Gabriel Le lun. 16 oct. 2023 à 09:06, gabriel robert < gabriel.hadrien.rob...@gmail.com> a écrit : > Dear Prof Greve, > > Many thanks for your reply, > Could you please confirm also the second part of the sentence ? " [...] > given the sample size this is likely to be marginal compared to the effect > size and results would still be interpretable... " > Sorry but experts are th only way to get a feeling about those analyses > without ground truth.. > Best wishes > > Gabriel Robert, MD, PhD, HDR > PU-PH, Pôle Hospitalo-Universitaire de Psychiatrie Adulte (PHUPA) > Psychiatrie de la personne âgée > Centre Hospitalier Guillaume Régnier, Rennes, France > U1228, UMR 60274 IRISA, Campus Beaulieu, Rennes, France > Google Scholar > <https://secure-web.cisco.com/1Rt5Z0rgc-Ek7_nUspuFTLA6AdeaggWV9PXaRvpC_L8V0m6UT-m4NTnM1MXD80a_29z6OXLxWN2woq9ra_-BAl3G9g-yMVbELfVnvUaJQyfTX8QFgVtZnder508xMoSJ5j-lemZGE-e_KFD0nnuK8_kvwh9SUO_wkTAysMVb-1ZSTHqgi5157my45w40xUoWG9Uyp7gU6urZQOyfSKJJfq3BS8j-zP8Kx9D6foK1hCMdmIJj1MQIuH-8sNSi3o2Qy5G0QW7D6kjMFcCp1aanqkOPpDOun3xce-1BTv-BBtq8yBG7a-bng3ZZJhmlKr87EgQM4sCS1_RZfeDWFGEcdlg/https%3A%2F%2Fscholar.google.fr%2Fcitations%3Fuser%3DYKM-owQAAAAJ%26hl%3Dfr> > Journées de Psychiatrie de la Personne âgée > <https://secure-web.cisco.com/136P6_NEbQGXL0v4UJ6br4Xtlmg1Jg2Ulquqe8XeW6nN0f22ZEo1L6RjxuOxRObPSvoGX37MrH30bWJtizO9ljcUpstDiXXCFxOZ7iuFurMm1Yzurpw_MnHW9Sn1wCbE2FNvIPb5Q9fRGqGm3sk1QssMfeJ2baSf8zlemh7pUCnDWEMM3Vr9RtIbC8zHb106kD7T0_RoYCJLPL6TzfMFv3fZtAJUGWn9TJ4OGq-m0Sv5Hfv7VqP33vuus-vn95a_ANHfbEhGshRJH4ntrXpUKrKyGJPHBXEvkq9FTgTtB-WyOgLS2bkCy1fE3W4hdBlZT/https%3A%2F%2Fcongresfrancaispsychiatrie.org%2Finscription-4eme-journee-de-psychiatrie-de-la-personne-agee-jppa%2F> > Société de Psychogériatrie et de Psychiatrie de la Personne Âgée (SF3PA) > <https://secure-web.cisco.com/1fADdG7jhtAXMJpy8JU7YTirOUZQb-xy_H5DMX3yePJ4xse1KqAj_xbLVyklCH4OfXr0onnozRkFNJW2jgTBJRC8ZXY25RhxZhU_brqG4UpDioRntS-BSE8qze5S0kFnuXOgKNp-E64J3MzdWehuC1uVWfFlzBqrqiufnF5AJduEu_6FCgJRLY9_w7WwbKHaI0YtBPI-g0SoBKUjv6uLQ5ui_N-gWCNANSMYKNNv7LYp0pjiqpnwdCNw3yCxCNl2P_ooWRczQa3CXrEBGKJV6QA96Jre6zJTWMELHjvmks27rs2Nd1b3ecsQA-3iFqnBF/https%3A%2F%2Fsf3pa.com%2F> > Institut de Neuroscience Clinique de Rennes > <https://secure-web.cisco.com/1J4FcdIJcMGtNG86PK8MjBhV7xmVSHdJnXGRfFTwBuciP_2ZglRcgAcaa25Igg9DnIaUM2jkxRhUdQF3EAIEStibEfyXbzeewUs1DS4lu488hV-O3eC37sJsToqFz06Vfe4DtSDgLb_ONhVIreZeutlRuOOmKhfU4xX_aEnNJnf_xB4HTGg-IgtFTFLq4VVu1p1sfTeZvR19-1MoswP2VEAMCf2RxLQq8A34OcHBM1soPCWhhf5jD6Awk7uFFI5CXSNdu3urjuWsAeo4oiMNtrJBt4RU4ByiI6fASKW7j1dOawtHv0iygtf-8FCKi428N/https%3A%2F%2Fwww.incr.fr%2F> > > > > Le lun. 16 oct. 2023 à 04:55, Douglas N. Greve <dgr...@mgh.harvard.edu> a > écrit : > >> yes, I think so too >> >> On 9/19/2023 5:07 PM, gabriel robert wrote: >> >> External Email - Use Caution >> Dear experts in longitudinal neuroimaging >> >> We carefully read the papers about possible biases introduced by treating >> timepoints images differently (Reuter and Fischl NI 2011, for example) to >> estimate unbiased anatomical and functional changes of brain development in >> healthy individuals. We took good note that treating each time point >> independently would remove asymmetry biases at the cost of reduced power. >> >> In our project, we would like to analyze about 800 scans both 3DT1, >> diffusion (FA preprocessed with fsl TBSS) and functional task BOLD at 3 >> time points (14 years-old, 19 years-old and 23 years-old). >> >> Each time point scans are preprocessed individually and normalized to a >> specific group-based template at the corresponding time point (not a >> within-subject midpoint symmetric space) and to the standard MNI space. >> >> Our question: We'd like to use a home-made study-specific multimodal >> atlas to resample ROI BOLD mean contrasts and fractional anisotropy at each >> time point but this atlas is *based on the last time point only (23 >> years-old).* Does this situation fall into the 'asymmetry-induced bias >> in longitudinal processing' ? >> >> Our feeling is most probably yes but given the sample size this is likely >> to be marginal compared to the effect size and results would still be >> interpretable... ? >> >> Many thanks for time, interest and insight, >> >> Best wishes >> >> Gabriel >> >> >> _______________________________________________ >> Freesurfer mailing >> listfreesur...@nmr.mgh.harvard.eduhttps://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer >> >> >> _______________________________________________ >> Freesurfer mailing list >> Freesurfer@nmr.mgh.harvard.edu >> https://secure-web.cisco.com/1-vMvaQaH0yuqnk8fsx7hyYmvbfyS40PPkC7pk1tfiGCtbkzR3h4HebIKCWucyAYQ8iRTGjJy2ynCveU3E5XwlgZuRvoBkeZxbqkGHJR0cLJbQIoE4VOf91-YQmFRvgnM9VFTPBUzTg525yI5frLhw84Hxe92xOXZm_OV5Xk_jIVjndmEndh09rWkp92QfMfLx-Mxvhah928lRtBwwEpa9KTMxoqsEFsOtuEkf-K4VNSxBCKndd3VCYxbQDdOmDIKcnFsGUIs_DW87CSK66FRmOWk0U--1GD5LaeGzJmuVmMulHlMGRhzFJWUxG1yTQg7YMRxUjcFT0i91DduyraXOg/https%3A%2F%2Fmail.nmr.mgh.harvard.edu%2Fmailman%2Flistinfo%2Ffreesurfer >> The information in this e-mail is intended only for the person to whom it >> is addressed. 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