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On 7/14/2023 4:15 PM, Carlos Alcocer wrote:

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Thank you for your response. If I wanted to calculate the surface area of this cortical ROI, would i pass lh.area.pial into <in>? Do i still use --accumulate flag?

Thank you,

Carlos

On Thu, Jun 15, 2023 at 5:17 PM Huang, Yujing <yhuan...@mgh.harvard.edu> wrote:

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    Hi Carlos,

    Your commands look correct to calculate mean cortical thickness.

    To calculate the total volume, pass lh.volume to –in <>, and
    specify –accumulate on the command line: *MailScanner has detected
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    Best,

    Yujing

    *From:* freesurfer-boun...@nmr.mgh.harvard.edu
    <freesurfer-boun...@nmr.mgh.harvard.edu> *On Behalf Of *Carlos Alcocer
    *Sent:* Thursday, June 15, 2023 11:36 AM
    *To:* Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
    *Subject:* [Freesurfer] Calculate cortical thickness of a
    volumetric ROI

    *        External Email - Use Caution *

    Hello,

    I am trying to calculate the cortical thickness of a volumetric
    ROI that I created that I have in subject space for every subject
    in my dataset. I was using *MailScanner has detected a possible
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    as a guide.

    Since, I already have the volumes in subject space. I did a
    modified pipeline and only did the following for each subject:
    1. mri_vol2surf --mov /path/to/ROI5.nii --regheader --projfrac-max
    0 1 0.1 --interp nearest --hemi lh --out lh.ROI5.mgh
    2. mri_segstats --seg $SUBJECTS_DIR/subjid/surf/lh.ROI5.mgh --in
    lh.thickness --sum segstats-ROI5.txt

    Does this make sense? Also, separately, is the volume that is also
    computed in this method accurate? I noticed that the volume is
    always equal to the number of voxels, which I assume a voxel is
    equal to 1mm^3? However, when looking at aseg.stats these volumes
    have different values from their number of voxels.

    Thank you,

    Carlos

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