Dear Anna,

There’s 3 factors affecting the results:

1. Atlas: we haven’t changed that in ages.
2. Optimization in segmentation code: there’s tiny differences in there but as 
long as you’ve used the same version for every case, you should be good.
3. Version of FS used to process the subject. This is crucial because the 
hippocampal module uses aseg.mgz for initialization. Again, if you have mixed 
versions, you should be good.

Cheers,

/E



Juan Eugenio Iglesias
www.jeiglesias.com<http://www.jeiglesias.com>


On Oct 20, 2022, at 2:38 PM, ANNA FINLEY 
<ajfinl...@wisc.edu<mailto:ajfinl...@wisc.edu>> wrote:

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Hello Freesurfer experts!

We have previously extracted hippocampal subfields and nuclei of the amygdala 
using the beta version of segmentHA_T1.sh routine with Freesurfer 6 beta. We 
are wondering if there is any reason to expect volumetric differences between 
the beta and current version of this routine? In other words, would it be 
necessary to rerun with the current version in Freesurfer 7, or are the initial 
values extracted with the beta version sufficient?

Thank you for your help!

Anna Finley

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