External Email - Use Caution This is not something we have typically done with T1w/T2w myelin mapping. Is there a reason you are especially concerned about these issues? We tend to find that issues with surface placement, which are more prevalent at 1mm isotropic than at higher resolutions, are a far bigger issue and I don’t know that PETsurfer will help with this because it is based on the surfaces themselves. I would recommend just sticking with the default HCP Pipelines approach for T1w/T2w myelin mapping.
Matt. From: <freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of Marina Fernández <marina.fdez.alva...@gmail.com> Reply-To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu> Date: Tuesday, May 24, 2022 at 10:54 AM To: "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu> Subject: [Freesurfer] Tissue fraction effects correction External Email - Use Caution Dear FS experts, We are planning to correct for tissue fraction effects on T1w/T2w ratio images using PETsurfer, setting the point spread function estimate to zero. My questions are: 1. Does it make sense to correct for tissue fraction effects on T1w/T2w ratio images even when T1w and T2w images were acquired using the same matrix size with identical voxel resolution (i.e., 1mm3)? 2. If that makes sense, which PVC method would work best for correcting tissue fraction effects (i.e., SGTM, MG, RBV) on structural MRI scans? Many thanks in advance. Best, Marina ________________________________ The materials in this message are private and may contain Protected Healthcare Information or other information of a sensitive nature. If you are not the intended recipient, be advised that any unauthorized use, disclosure, copying or the taking of any action in reliance on the contents of this information is strictly prohibited. If you have received this email in error, please immediately notify the sender via telephone or return mail.
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