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Dear FS experts,

We are planning to correct for tissue fraction effects on T1w/T2w ratio
images using PETsurfer, setting the point spread function estimate to
zero. My questions are:

1. Does it make sense to correct for tissue fraction effects on T1w/T2w
ratio images even when T1w and T2w images were acquired using the same
matrix size with identical voxel resolution (i.e., 1mm3)?

2. If that makes sense, which PVC method would work best for correcting
tissue fraction effects (i.e., SGTM, MG, RBV) on structural MRI scans?

Many thanks in advance.

Best,
Marina
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