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Hi AJ,

The longitudinal stream does not account for inter-scanner variability, but
does reduce biases related to registering subsequent timepoints to the
initial one.

Perhaps longitudinal experts could confirm, but I would run the
longitudinal stream, then account for scanner differences afterwards.

-Paul

On Sun, Jul 4, 2021 at 10:03 AM AJ <ajcns1...@gmail.com> wrote:

>         External Email - Use Caution
>
> Hi,
> I am running Freesurfer on longitudinal datasets all obtained on 3T
> scanners. Unfortunately,  many of the MRIs were done on different
> scanners,  Phillips and GE.
> Would longitudinal pipeline help reduced scanner variability or should I
> process crossectionally each time point separately and normalize these time
> points with eTIV?
>
> Many thanks
> AJ
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