Hi Dylan

Sorry, did anyone ever answer this? The .lta files contain the transform but 
also information on the coordinate systems that they are in. I think that the 
standard talairach one is voxel to voxel, so it would indeed change with the 
image fov. There are tools for converting ltas to ras-to-ras, which  I think is 
what you want (although you will need to make sure you get the correct ras 
space), but perhaps someone else can comment on this since I don't remember the 
details?

Cheers
Bruce

-----Original Message-----
From: freesurfer-boun...@nmr.mgh.harvard.edu 
<freesurfer-boun...@nmr.mgh.harvard.edu> On Behalf Of Tisdall, Dylan
Sent: Thursday, December 24, 2020 11:41 AM
To: freesurfer@nmr.mgh.harvard.edu
Subject: [Freesurfer] talairach.lta coordinate spaces

        External Email - Use Caution        

Hi list,

I'm trying to understand whether the talairach.lta transform is from the 
image-axes RAS to talairach or the scanner-axes RAS to talairach. Basically, if 
I rotate the imaging FOV and scan the same subject, should I expect that to 
change talairach.lta or not? My confusion stems from the discrepancy between 
what the scanner terms RAS coordinates (aligned to the gradient axes) vs. what 
might be plausibly called RAS in the image coordinates (aligned to the FOV 
axes).

The underlying goal here is to try to evaluate how gradient-axis-aligned 
someone's head was when they were loaded in the scanner.


Thanks,
Dylan

---
Dylan Tisdall, PhD
Research Assistant Professor
Department of Radiology
Perelman School of Medicine
University of Pennsylvania

Room D406 Richards Medical Labs
3700 Hamilton Walk
Philadelphia, PA 19104



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