Hi Yezhe It depends a lot on what your resolution, read out direction, bandwidth and field strength are. We generally fix these with T2 or FLASH scans at the same resolution/geometry/readout as the T1. Otherwise they are pretty tough as the dura is close enough to the gray matter that you can’t see any space between them
Cheers Bruce From: freesurfer-boun...@nmr.mgh.harvard.edu <freesurfer-boun...@nmr.mgh.harvard.edu> On Behalf Of LIN, Yezhe Sent: Monday, November 30, 2020 5:10 PM To: freesurfer <freesurfer@nmr.mgh.harvard.edu> Subject: [Freesurfer] Freesurfer skullstripping error External Email - Use Caution Dear Freesurfer users, Hope this finds you well. I preprocessed our dataset with recon-all <subj> -s <subj> -all -qcache and found a number of our subjects had different levels of skullstrip errors. I tried fixing them by a couple of different approaches, such as -gcut and adjusted watershed threshold, but they both failed to fix the overlapping of dura mater (Fig1 and 2). I tried two methods on different subjects and received the same outcome. I wonder if you have any ideas to fix this error. At this point, for some who had less skullstripping, I can erase them manually and run -autorecon-pial or -make. But for the others with multiple locations of skullstripping (like Fig 3 and 4), do you have any ideas on how to approach to them at a systemic level? Also I found the skullstripping error in over half of our subjects, is it normal that we have a such proportion? Thank you so much! ------------------ Best regards, Yezhe Yezhe Lin, MD MMed (she/her/hers) Postdoctoral Associate, Department of Psychiatry University of Rochester Medical Center yezhe.lin....@gmail.com<mailto:yezhe.lin....@gmail.com> Twitter<https://secure-web.cisco.com/17wBDBOCFmouG2s48nVWmz-vtBr4ZdcKyF8LdUP3ubrRwDQczpm4GpOeJX8y9BVGMRDS3hknZ-VHMl7Mpew7MEMYptkhA86r0KsD3iwPADFZYwCP0wxhuxurWl7QVvY-iKE9rh-IjjIqsk-tgiFqsn1hWbEH81U5odkPQ55wh4CEqMgfm-cSZSuaDsqkZKqwZUEozlWj1ZaRsw8-u0HAfV0dr1to__qlJ3caSexRdjxciXDNNso4HC-jOlPghIUXCedxdkrpeD-QiAcrCzB-gJg/https%3A%2F%2Ftwitter.com%2FLinYezhe>: @LinYezhe | LinkedIn<https://secure-web.cisco.com/11z7MNr4cmxXqrne4KcsfCzlNqe69kxiyCzG4wHKz5Ap2hkVCq7WQE3bUD0nxI3_devi7THRad8MWIkFCE8TIJsGs63B1KKBwx8i16T9hRbwmWuZi1-8rDjYgn8fXpWJ6UHh2TQ4hr199_npMHLrGZcY0k1LHUXCIoTxLlrzhbcMLqsMHFUpNs7rbXmCIijBujwG_V-SFYHX0ZQgm_P6tvN_6l2TuqIGq51X2K0M489TLi7tilzKUefrQ7rs_rIOsZDL0UF35gildP4UD5s_vLg/https%3A%2F%2Fwww.linkedin.com%2Fin%2Fyezhe-lin-md-mm-7063b2a1%2F> | Researchgate<https://secure-web.cisco.com/1izwT1sMSoKIcMU2d5YWspFhUDtyiXLrkLArb2WuhXY_thz7lEEHjRyirwimP3Vugr6-mte-mOTSXr5fF83_ci3Qfe_rxFYckK5SaisS5HzmQ3bxMPDMOYNqvng1DS9OgDGAiXb-i17FzeUpR5j_DiuNd5mYs33onTXfi3d4EddqwCOEfjj6m4LbeQAomOMxs06OQ2d8rIPlUPGjELGFQz8xsHlNuDNzKt-daYiJYAs1kgHgxtEF9vM-ssT2gYGaIzf2_qdHfnThVsbwdgrKCeQ/https%3A%2F%2Fwww.researchgate.net%2Fprofile%2FYezhe_Lin>
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