as you note, the gtmseg.mgz has higher resolution and several new ROIs. the higher res is for partial volume correction. The inclusion of pons to for the possibility of using it as a reference region, which often happens in AD studies of FDG. Vermis is for use in serotonin studies so it can be excluded from the rest of cerebellar cortex as vermis might have some receptors there making is inappropriate to use as a reference region.

On 10/26/2020 9:55 PM, 蒋袁芳 wrote:

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Hello Freesurfer Developers,

I have some questions about why the first step of PETSurfer needs to create gtmseg.mgz segmentation.

I noticed that the differences between gtmseg.mgz and aseg.mgz are the gtmseg.mgz has a higher resolution and also to separate the pons and the vermis from the brainstem and the cerebellar. I would like to know whether the reason to create the gtmseg.mgz segmentation is because the ROI is based on the Pons?

If so, I also have read some other articles that the ROI is based in other regions. Why does the Freesurfer choose Pons instead? Also, what is the purpose of separating the vermis from the cerebellar? Is the reason to create the gtmseg.mgz segmentation just for the system to run the PVC?

looking forward to your reply.

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