Hi Laura, it looks like there is a bug in v6 that does not transfer the edits correctly. This is fixed in v7, but I'm looking into getting you a version of mri_mask that will work in v6.
doug

On 6/23/2020 1:49 PM, Danielian, Laura (NIH/NINDS) [E] wrote:

        External Email - Use Caution

OK thanks. Do you recommend that I re-run this for every subject that I did these cerebellar edits on since it ended up editing brain.finalsurfs.mgz?  I have a handful of other data sets where it didn’t affect the longitudinal surfaces, but upon further inspection it’s clear that those cross-sectional edits within the cerebellum carried over to brain.finalsurfs.mgz in the longitudinal data sets.

Also, I’m still not sure how the edits I made on the brain.finalsurfs.manedit.mgz volumes got transferred over to the original.  Do you have any suggestions for how this happened and how to avoid doing this in the future?

Thanks,

Laura

*From: *"Douglas N. Greve" <dgr...@mgh.harvard.edu>
*Reply-To: *Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
*Date: *Tuesday, June 23, 2020 at 10:18 AM
*To: *"freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
*Subject: *Re: [Freesurfer] Longitudinal Stream Problem

If you run this, it will create a new brain.finalsurfs and rerun just what you need to rerun recon-all -s subject -autorecon2 -nogcareg -nocalabel -nonormalization2 -autorecon3

On 6/22/2020 1:20 PM, Danielian, Laura (NIH/NINDS) [E] wrote:

    *        External Email - Use Caution *

    Interesting – I never did any editing directly on the original
    brain.finalsurfs.mgz.  I only did cerebellar edits on the
    brain.finalsurfs.manedit.mgz copy of brain.finalsurfs.mgz.  Looks
    like those edits copied over somehow.

    Regardless, it sounds like this will be easy to correct.  Where
    can I find an unedited copy of brain.finalsurfs.mgz and when/how
    would I reintegrate that into the processing stream?

    Thanks,

    Laura

    *From: *"Douglas N. Greve" <dgr...@mgh.harvard.edu>
    <mailto:dgr...@mgh.harvard.edu>
    *Reply-To: *Freesurfer support list
    <freesurfer@nmr.mgh.harvard.edu>
    <mailto:freesurfer@nmr.mgh.harvard.edu>
    *Date: *Monday, June 22, 2020 at 12:13 PM
    *To: *"freesurfer@nmr.mgh.harvard.edu"
    <mailto:freesurfer@nmr.mgh.harvard.edu>
    <freesurfer@nmr.mgh.harvard.edu>
    <mailto:freesurfer@nmr.mgh.harvard.edu>
    *Subject: *Re: [Freesurfer] Longitudinal Stream Problem


    It looks like someone edited the brain.finalsurfs.mgz. In the
    attached is the image of the brain.final... You can see where the
    brain is missing. The white surface (green line) stops at that
    edge. When I used the unedited brain, the surfaces went to the
    right place (yellow surface)

    On 6/22/2020 9:21 AM, Danielian, Laura (NIH/NINDS) [E] wrote:

        *        External Email - Use Caution *

        Thanks Douglas.  I could send other problem data sets too if
        it would help.  Just let me know.

        Thanks,

        Laura

        *From: *"Douglas N. Greve" <dgr...@mgh.harvard.edu>
        <mailto:dgr...@mgh.harvard.edu>
        *Reply-To: *Freesurfer support list
        <freesurfer@nmr.mgh.harvard.edu>
        <mailto:freesurfer@nmr.mgh.harvard.edu>
        *Date: *Friday, June 19, 2020 at 6:10 PM
        *To: *"freesurfer@nmr.mgh.harvard.edu"
        <mailto:freesurfer@nmr.mgh.harvard.edu>
        <freesurfer@nmr.mgh.harvard.edu>
        <mailto:freesurfer@nmr.mgh.harvard.edu>
        *Subject: *Re: [Freesurfer] Longitudinal Stream Problem

        OK, I have it now and am able to verify the problem. It's
        really strange -- I don't know why it is behaving like this.
        It may take me a few days to dig into.

        On 6/18/2020 11:39 AM, Danielian, Laura (NIH/NINDS) [E] wrote:

            *        External Email - Use Caution *

            Sorry I’m not sure why it didn’t upload.  I just tried it
            again.  danielianall.tar.gz  - Should include all parts. 
            EM2 is the cross-sectional.  EM is the base. EM2.long.EM
            is the long.  I also tried sending just the base again. 
            danielianbase.tar.gz.

            Thanks,

            Laura

            *From: *"Douglas N. Greve" <dgr...@mgh.harvard.edu>
            <mailto:dgr...@mgh.harvard.edu>
            *Reply-To: *Freesurfer support list
            <freesurfer@nmr.mgh.harvard.edu>
            <mailto:freesurfer@nmr.mgh.harvard.edu>
            *Date: *Thursday, June 18, 2020 at 9:12 AM
            *To: *"freesurfer@nmr.mgh.harvard.edu"
            <mailto:freesurfer@nmr.mgh.harvard.edu>
            <freesurfer@nmr.mgh.harvard.edu>
            <mailto:freesurfer@nmr.mgh.harvard.edu>
            *Subject: *Re: [Freesurfer] Longitudinal Stream Problem

            I have not seen that file appear. Can you re-upload it?

            On 6/16/2020 10:19 AM, Danielian, Laura (NIH/NINDS) [E] wrote:

                *        External Email - Use Caution *

                Hi Douglas,

                OK I just uploaded the base separately. 
                danielianbase.tar.gz  I thought it was part of the
                original bundle.  Sorry!

                Laura

                *From: *"Douglas N. Greve" <dgr...@mgh.harvard.edu>
                <mailto:dgr...@mgh.harvard.edu>
                *Reply-To: *Freesurfer support list
                <freesurfer@nmr.mgh.harvard.edu>
                <mailto:freesurfer@nmr.mgh.harvard.edu>
                *Date: *Tuesday, June 16, 2020 at 10:10 AM
                *To: *"freesurfer@nmr.mgh.harvard.edu"
                <mailto:freesurfer@nmr.mgh.harvard.edu>
                <freesurfer@nmr.mgh.harvard.edu>
                <mailto:freesurfer@nmr.mgh.harvard.edu>
                *Subject: *Re: [Freesurfer] Longitudinal Stream Problem

                I have your data, but it does not have the base image.
                Can you upload that as well?

                On 6/15/2020 5:15 PM, Danielian, Laura (NIH/NINDS) [E]
                wrote:

                    *        External Email - Use Caution *

                    Hi Douglas,

                    I just upload the files as danielian.tar.gz.  I
                    didn’t notice any damage or artifact on this
                    particular brain or the others that had this same
                    problem.  This subject is a healthy control and
                    most of the subjects (3 of 4) that are having this
                    problem are healthy.  For each we used 2 T1s for
                    the original cross-sectional input.  The cross was
                    reconstructed fine as was the base and the 2 other
                    longitudinal timepoints for this same subject. The
                    same is the case with the others I’m having
                    trouble with – all of the their other timepoints
                    are fine for the cross/base/longitudinal
                    surfaces.  The warped surfaces are always lower
                    posterior (cerebellum adjacent) and sometimes also
                    temporal.  Upper cortical and frontal regions are
                    unaffected.

                    Thanks for your help!

                    Laura

                    *From: *"Douglas N. Greve"
                    <dgr...@mgh.harvard.edu>
                    <mailto:dgr...@mgh.harvard.edu>
                    *Reply-To: *Freesurfer support list
                    <freesurfer@nmr.mgh.harvard.edu>
                    <mailto:freesurfer@nmr.mgh.harvard.edu>
                    *Date: *Friday, June 12, 2020 at 10:35 AM
                    *To: *"freesurfer@nmr.mgh.harvard.edu"
                    <mailto:freesurfer@nmr.mgh.harvard.edu>
                    <freesurfer@nmr.mgh.harvard.edu>
                    <mailto:freesurfer@nmr.mgh.harvard.edu>
                    *Subject: *Re: [Freesurfer] Longitudinal Stream
                    Problem

                    Hard to tell from just that view. Was there a lot
                    of brain change with that time point? Or was there
                    an MRI artifact? If no to both, then you can
                    upload all the cross, the base, and that one long.
                    Follow instructions below (you can make one
                    tarball for all subjects)

                    From the linux command line,
                    Create the file you want to upload, eg,
                    cd $SUBJECTS_DIR
                    tar cvfz subjects.tar.gz ./subject1 ./subject2
                    Now log  into our anonymous FTP site:
                    ftp surfer.nmr.mgh.harvard.edu
                    It will ask you for a user name: use "anonymous"
                    (no quotes)
                    It will ask you for a password: use "anonymous"
                    (no quotes)
                    cd transfer/incoming
                    binary
                    put subjects.tar.gz
                    Send an email that the file has been and the name
                    of the file.









                    On 6/9/2020 6:32 PM, Danielian, Laura (NIH/NINDS)
                    [E] wrote:

                        *        External Email - Use Caution *

                        Hi, I’ve finished processing a data set that
                        included longitudinal data and I’m having a
                        problem with a small percentage of the
                        longitudinal timepoints.  To review what I’ve
                        done, I edited all of the individual
                        (cross-sectional) timepoints until the wm and
                        pial surfaces were correct, then created the
                        base and edited that until it looked good, and
                        then created the longitudinal files for each
                        cross-sectional timepoint.  Most of these did
                        not need editing and some needed slight edits
                        to either wm or brainmask which corrected the
                        longitudinal surfaces.

                        However, in a small handful of cases, the
                        wm/pial surfaces were so distorted that
                        editing would not fix the problem.  In these
                        cases, longitudinal surfaces were very
                        different from both the original cross-section
                        and base.  I’ve tried to attach a file that
                        shows an example – it might only affect a
                        small portion of the brain but in these cases
                        I don’t think I could edit it to improve the
                        surfaces.  In the example I attached, red/blue
                        are from the long file and pink/lt blue are
                        from the base.

                        Do you have any suggestions for why this might
                        be happening and how to fix it?  I’m running v6.0.

                        Thanks!

                        Laura Danielian








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