Hi Brian,

I honestly can’t tell the difference, even when the high dpi rendering is 
turned on. The volume is low res to begin with. There is a smooth display check 
box you can try in freeview. It will remove the pixelation of the rendering. 

Best
Ruopeng

> On Apr 14, 2020, at 4:28 PM, Renner, Brian <brian.ren...@cshs.org> wrote:
> 
>         External Email - Use Caution        
> Hi Rupoeng!
> 
> Attached is a direct flair opening in same without flags, freeview (L) 
> fsleyes (R), set with 0-168 min-max for each window (fig 1). I did notice a 
> tick box in fsleyes was set to "render in high DPI" was checked (fig 2), so I 
> unchecked it for fig 1. 
> 
> <Screen Shot 2020-04-14 at 1.27.06 PM.png>
> fig 1
> 
> <Screen Shot 2020-04-14 at 1.23.18 PM.png>
> fig 2.
> 
> Perhaps that is the culprit; is there a similar render mode for freeview or 
> is that the driver not optimized as Andrew previously wrote?
> 
> Much thanks all!
> 
> BR
> From: freesurfer-boun...@nmr.mgh.harvard.edu 
> <freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of Ruopeng Wang 
> <rpw...@nmr.mgh.harvard.edu>
> Sent: Tuesday, April 14, 2020 11:10 AM
> To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
> Subject: Re: [Freesurfer] [External] Re: Freesurfer display resolution very 
> low compared to other viewers
>  
> Hi Brian,
> 
> Can you load a single volume in freeview to compare? Maybe also use similar 
> window/level? The one in the picture appears smoothed to me (may due to 
> trilinear sampling if it is not the first loaded volume).
> 
> Best,
> Ruopeng
> 
> 
>> On Apr 14, 2020, at 1:14 PM, Renner, Brian <brian.ren...@cshs.org 
>> <mailto:brian.ren...@cshs.org>> wrote:
>> 
>>         External Email - Use Caution        
>> Hey Andrew;
>> 
>> Thanks for the response! To answer your questions, yes, We’re all 
>> respectively on Macbook Pro retina displays. I hadn't compared the 
>> visualization on a Windows machine, though I ostensibly could in the near 
>> future. I have loaded up single vs. multiple volumes and noticed what you 
>> say; would it be best to load the hypothetical highest resolution scan 
>> first? ie. freeview -v highest.nii lower.nii. lowest.nii. --trilinear?
>> 
>> An example picture of this is shown below, with a standard 1mm^3 t2 flair 
>> loaded in freeview with a higher resolution t2* as the first loaded scan, 
>> ie. on the left freeview -v t2*file flair --trilinear vs. fsleyes t2*file 
>> flair on the right:
>> 
>> <Screen Shot 2020-04-14 at 9.40.57 AM.png>
>> Fig 1. This is the flair file compared side by side (fv --trilinear vs. 
>> fsleyes, respectively).
>> 
>> <Screen Shot 2020-04-14 at 9.43.58 AM.png>
>> Fig 2. This is the t2*file (0.65mm voxel width), which has both noticeable 
>> quality drop and a different baseline intensity threshold at baseline 
>> between freeview and fsleyes. 
>> 
>> <Screen Shot 2020-04-14 at 10.00.10 AM.png>
>> Fig 3. This is the flair --trilinear vs. flair (noflags) vs. fsleyes flair, 
>> respectively.
>> 
>>  Let me know what you think, and again thank you for the response!
>> 
>> BR
>> 
>> From: freesurfer-boun...@nmr.mgh.harvard.edu 
>> <mailto:freesurfer-boun...@nmr.mgh.harvard.edu> 
>> <freesurfer-boun...@nmr.mgh.harvard.edu 
>> <mailto:freesurfer-boun...@nmr.mgh.harvard.edu>> on behalf of Hoopes, Andrew 
>> <ahoo...@mgh.harvard.edu <mailto:ahoo...@mgh.harvard.edu>>
>> Sent: Tuesday, April 14, 2020 9:25:08 AM
>> To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu 
>> <mailto:freesurfer@nmr.mgh.harvard.edu>>
>> Subject: [External] Re: [Freesurfer] Freesurfer display resolution very low 
>> compared to other viewers
>>  
>> Hi Brian,
>>  
>> A couple questions - are you visualizing on a mac retina screen? If so, 
>> there will be a slight decrease from the standard resolution because the 
>> underlying rendering library that we use unfortunately does not support 
>> retina capabilities at this time. Also, are you loading single or multiple 
>> volumes? Freeview uses the first volume loaded as the base image geometry, 
>> and all the following volumes are resampled (if necessary) into this base 
>> geometry using nearest neighbor interpolation. So if you’re working with 
>> different-resolution images, it might help to enable linear interpolation as 
>> the default resampling method by using the `--trilinear` freeview flag. If 
>> that’s not the case, it’d be helpful to see a couple screenshots of the 
>> issue.
>>  
>> Hope that helps,
>> Andrew
>>  
>> From: <freesurfer-boun...@nmr.mgh.harvard.edu 
>> <mailto:freesurfer-boun...@nmr.mgh.harvard.edu>> on behalf of "Renner, 
>> Brian" <brian.ren...@cshs.org <mailto:brian.ren...@cshs.org>>
>> Reply-To: FS Help <freesurfer@nmr.mgh.harvard.edu 
>> <mailto:freesurfer@nmr.mgh.harvard.edu>>
>> Date: Monday, April 13, 2020 at 8:54 PM
>> To: FS Help <freesurfer@nmr.mgh.harvard.edu 
>> <mailto:freesurfer@nmr.mgh.harvard.edu>>
>> Subject: [Freesurfer] Freesurfer display resolution very low compared to 
>> other viewers
>>  
>>         External Email - Use Caution        
>> Hello all! 
>>  
>> Inaugural message to the list; I will attempt to be brief with the project 
>> description.
>>  
>> The setup is consistent between both versions 6.0.0 and 7.0.0-beta, run on a 
>> high performance cluster, accessed through macOS terminal + Xquartz, most 
>> recent versions all.
>>  
>> As it stands, our group is attempting to do subfield analysis of hippocampal 
>> analysis and lesion measurement in MS subjects. We have noticed that there 
>> is a major discrepancy of resolutions between files, which has irked some of 
>> our physicians undertaking the lesion measurement. We need to resolve the 
>> lesions down to 3mm and have noticed the quality between freeview and 
>> fsleyes of the same nifti files will yield much lower display resolution. 
>> This is true for most scans, though it has been compared using 1mm T2 FLAIR 
>> sequences as well as T2* sequences with 0.65mm voxel space. I have been 
>> attempting to find a workaround as the current solution for the physicians 
>> is to look at the files in fsleyes and then measure them with the ruler tool 
>> in freeview. I can send supporting pictures as necessary. 
>>  
>> Thank you in advance for any thoughts you may have!
>>  
>> BR
>>  
>> --
>> Brian Renner, MD
>> Research Associate, Neurology 
>> brian.ren...@cshs.org <mailto:brian.ren...@cshs.org>
>> 
>> Cedars-Sinai
>> 127 S. San Vicente Blvd, Suite A6600  :  Los Angeles CA 90048
>> office 310-423-1589  :  mobile 310-658-3492  :  cedars-sinai.org 
>> <https://www.cedars-sinai.org/> 
>>  
>> 
>> 
>> IMPORTANT WARNING: This message is intended for the use of the person or 
>> entity to which it is addressed and may contain information that is 
>> privileged and confidential, the disclosure of which is governed by 
>> applicable law. If the reader of this message is not the intended recipient, 
>> or the employee or agent responsible for delivering it to the intended 
>> recipient, you are hereby notified that any dissemination, distribution or 
>> copying of this information is strictly prohibited. Thank you for your 
>> cooperation.
>> <Screen Shot 2020-04-14 at 9.40.57 
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