Sorry, what is "pc1"?
On 1/14/2020 9:44 AM, Swati Rane wrote:
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Hello,
I was wondering if someone could answer my question below
Can I use mri_glmfit-sim after mri_glmfit on the longitudinal pc1 files.
Are there any set of parameters that should be set differently when using pc1
instead of thickness files?
Thanks!
Swati
____________________________________________
Swati Rane Levendovszky, PhD
Interim Director,Diagnostic Imaging Sciences Center
Assistant Professor,Integrated Brain Imaging Center
Radiology
University of Washington
Box 357115 | AA035 HSB | Seattle, WA 98195
srle...@uw.edu<mailto:srle...@uw.edu> | Ph: 206 543 6159
Web: https://sites.google.com/site/uwswatirane/
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From:
<freesurfer-boun...@nmr.mgh.harvard.edu><mailto:freesurfer-boun...@nmr.mgh.harvard.edu>
on behalf of Swati Rane <srle...@uw.edu><mailto:srle...@uw.edu>
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<freesurfer@nmr.mgh.harvard.edu><mailto:freesurfer@nmr.mgh.harvard.edu>
Date: Friday, January 10, 2020 at 10:06 AM
To: "freesurfer@nmr.mgh.harvard.edu"<mailto:freesurfer@nmr.mgh.harvard.edu>
<freesurfer@nmr.mgh.harvard.edu><mailto:freesurfer@nmr.mgh.harvard.edu>
Subject: [Freesurfer] mri_glmfit-sim for longitudinal pipelines
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Hello FreeSurfer Developers,
I'm attempting to compare longitudinal cortical thinning rates (pc1) between 3
groups using mri_glmfit using FreeSurfer 6.0. The tutorial suggests that you
could use the multiple comparisons corrections that come with it but does not
comment on using the mri_glmfit-sim option.
I just want to confirm whether there is anything prohibiting me from using
mri_glmfit-sim. Are there any set of parameters that should be set differently
when using pc-1 instead of thickness files?
Also, would you do a stricter correction and stick to the longitudinal model or
prefer the linear mixed effects model and do a FDR? How do you decide between
the two?
Thanks!
Swati
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