External Email - Use Caution Hello,
I was wondering if someone could answer my question below Can I use mri_glmfit-sim after mri_glmfit on the longitudinal pc1 files. Are there any set of parameters that should be set differently when using pc1 instead of thickness files? Thanks! Swati ____________________________________________ Swati Rane Levendovszky, PhD Interim Director, Diagnostic Imaging Sciences Center Assistant Professor, Integrated Brain Imaging Center Radiology University of Washington Box 357115 | AA035 HSB | Seattle, WA 98195 srle...@uw.edu<mailto:srle...@uw.edu> | Ph: 206 543 6159 Web: https://sites.google.com/site/uwswatirane/ ____________________________________________ From: <freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of Swati Rane <srle...@uw.edu> Reply-To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu> Date: Friday, January 10, 2020 at 10:06 AM To: "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu> Subject: [Freesurfer] mri_glmfit-sim for longitudinal pipelines External Email - Use Caution Hello FreeSurfer Developers, I'm attempting to compare longitudinal cortical thinning rates (pc1) between 3 groups using mri_glmfit using FreeSurfer 6.0. The tutorial suggests that you could use the multiple comparisons corrections that come with it but does not comment on using the mri_glmfit-sim option. I just want to confirm whether there is anything prohibiting me from using mri_glmfit-sim. Are there any set of parameters that should be set differently when using pc-1 instead of thickness files? Also, would you do a stricter correction and stick to the longitudinal model or prefer the linear mixed effects model and do a FDR? How do you decide between the two? Thanks! Swati
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