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Dear all, I read previous threads on the list concerning the use of 'total measures' (e.g., mean thickness, total brain volune, total area) as covariates in FreeSurfer's group analysis Given that FreeSurfer analyses brain hemispheres separately, would it make more sense to use hemispheric values (i.e., lh total area in the lh area analysis and rh total area in rh area analysis) than the mean cortical value (e.g., mean between lh and rh total area in both lh and rh analyses)? Best, Pedro.
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