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Hi Dr Greve,
I would like to use petsurfet to do kinetic modeling (KM), the pipeline is
straightforward and easy to use. Thank you so much! I would appreciate any
clarifications relevant to my questions bellow:
1) I understand that the flag "--km-ref" define the reference region for
normalizing PET signal. in the linear below the reference region is cerebellum
cortex. If we need to normalize to occipital just we change the numbers based
on labels in aparc+aseg atlas?
--km-ref 8 47 --km-hb 11 12 13 50 51 52 --no-rescale
2) --km-hb define the high binding regions. Are these regions represent the
regions that are pathologically involved where we expect it to have higher PET
signal OR it represent the regions where PET tracer has the maximum binding in
general regardless of pathology? I mean every tracer have high level in
specific regions in the brain is this what the flag is referring too?
Thanks for any clarification,
John
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