Can you send all the things that mri_glmfit suggests sending? On 2/6/19 5:16 AM, Michal Tanzer wrote: > > External Email - Use Caution > > Hello FreeSurfer Developers, > > I’m attempting to compute mri_glmfit to correlate cortical thickness > with my dependent var while controlling for age, gender, iq and > MRIcenter (2 centers). I don’t have any interactions or assumptions on > group differences so I am using DOSS design (with fsgd file) > > I have two questions regarding the analysis, which I couldn’t find in > the archives ( I copied the error and attaching the fsgd file) > > When I am trying to control for the different variables using 4 > classes (Center1Female, Center2 Female, Center1Male, Center2,Male) > (Correlation matrix 0, 0 , 0 , 0 , 0, 0, 1) I am getting the error: > > ERROR: matrix is ill-conditioned or badly scaled, condno = 1e+10 > > -------------------------------- > Possible problem with experimental design: > Check for duplicate entries and/or lack of range of > continuous variables within a class. > If you seek help with this problem, make sure to send: > 1. Your command line: > mri_glmfit.bin --y lh.ext.thickness.10.mgh --fsgd EXT2.fsgd doss > --C EXT2.mtx --surf fsaverage lh --cortex --glmdir lh.ext2.glmdir > 2. The FSGD file (if using one) > 3. And the design matrix above > Attempting to diagnose further > SumSq: Min=0.000000 (col 1), Max=0.000000 (col 0) > Column 1, all values are 0 > -- > > However when I am not using the 2 sites as classes and using just the > gender as a class (0,0,0,0,1) everything runs without errors. Is there > any other way to control for the MRIsite? > > Thank you for your help with this matter > Best wishes > Michal > > -- > Michal Tanzer, PhD > > Postdoctoral fellow; Clinical Psychologist. > Research Department of Clinical, Educational and Health Psychology, > University College London, > United Kingdom > > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
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