Hi Riccardo

when you say "compute the volume", what exactly do you mean? If you want the interior volume of the two surfaces, you can use mris_volume, which uses the divergance formula to do the calculation

cheers
Bruce


On Tue, 30 Oct 2018, Riccardo Falsini wrote:


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Dear Freesurfer experts,
Hello, I am a student currently working in Frank Guenther's lab at Boston 
University. 
I am quite new to freesurfer, so forgive me if the following question may be 
elementary.

I am interested in using freesurfer to compare the level of atrophy (preferably 
for different brain
areas) in an individual subject to several controls. I'm wondering if there is 
any way to determine
the volume of the '?h.pial-outer-smoothed', and corresponding '?h.pial' file 
generated from running
the 'recon-all -s <subj> -localGI' command. The idea is that I could generate a 
metric representing
a general level of atrophy in subjects by comparing these two volumes (or by 
comparing the
'?h.pial-outer-smoothed' to intracranial volume), however, I have been unable 
to find a way to
retrieve these values. Does anyone have any suggestions? I would greatly 
appreciate any help in this
regard.

Thank you for your help!

Best,
Riccardo Falsini

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