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Douglas,

Thanks for your quick response. If I only want the information of cortical 
thickness, surface area, volume for various cortical regions and LGI, then the 
Freesurfer template is good enough and I don’t need to apply my own template. 
This is really helpful. Is there any documents that you will recommend to get a 
better understanding about Freesurfer? 

Thanks a lot.

Ting 
> On Apr 19, 2018, at 12:39 PM, Douglas N. Greve <dgr...@mgh.harvard.edu> wrote:
> 
> If you want to do a surface-based analysis, then you don't need to have 
> an accurate volume template. If you want to use a custom volume-based 
> segmentation atlas, then you'll need to run gcatrain and gca-apply
> 
> 
> On 04/19/2018 01:28 PM, Ting Li wrote:
>>         External Email - Use Caution
>> 
>> Douglas,
>> 
>> Sorry for bother you again. Our group want to study a cohort children’s 
>> brain using Freesurfer. We prefer to register our subjects to a custom 
>> children template. The template basically is an average of all the subjects 
>> we are going to study. It is constructed by ANTs. The format is nii.gz. My 
>> questions is where I should mention this registration template in the 
>> command Recon-all?  or how to get the cortical thickness, surface area and 
>> volume for various cortical regions for all subjects and perform the GLM 
>> analyses?
>> 
>> In Freesurfer, there is a command of making own template for registration. 
>> If I generate my template from there, how can I run recon-all for the next 
>> to make sure my subjects all register to this template? and how to get the 
>> cortical thickness, surface area and volume for various cortical regions for 
>> all subjects and perform the GLM analyses?
>> 
>> I really need your help for this. Thanks for your time.
>> 
>> Best,
>> Ting
>>> On Apr 19, 2018, at 11:42 AM, Ting Li <tx...@ualr.edu> wrote:
>>> 
>>> Douglas,
>>> 
>>> Thank you so much for your response. My atlas is nii.gz format. What should 
>>> I do to get the cortical thickness, surface area and volume for various 
>>> cortical regions? Thanks in advance.
>>> 
>>> Best,
>>> Ting
>>> 
>>> 
>>>> On Apr 19, 2018, at 11:28 AM, Douglas N. Greve <dgr...@mgh.harvard.edu> 
>>>> wrote:
>>>> 
>>>> Is the atlas in GCA format? If so, then you can use gca-apply
>>>> 
>>>> 
>>>> On 04/19/2018 10:09 AM, Ting Li wrote:
>>>>> Hi Freesurfer Experts,
>>>>> 
>>>>> We want to run recon-all with a custom atlas which is generated from
>>>>> ANTs multivariate template construction. What is the right procedure
>>>>> to run recon-all? Run recon-all to my atlas itself first and them use
>>>>> this output as a template or I use the custom template directly. I
>>>>> looked up your email database to search related topic and got lost. I
>>>>> have sent another email to your group and no response received. Please
>>>>> help me.
>>>>> 
>>>>> Thanks for you time. I look forward to hearing from you.
>>>>> 
>>>>> Best,
>>>>> Ting
>>>>> 
>>>>> 
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