Stop sending me this shit

> Wiadomość napisana przez Kai Ohmstedt <kai.ohmst...@googlemail.com> w dniu 
> 13.03.2018, o godz. 02:02:
> 
> Hi Douglas,
> 
> thank you for the explanation of the contrasts, this helped a lot!
> 
> 
> All the best,
> 
> Kai 
> 
> 2018-03-12 18:20 GMT+01:00 Douglas N. Greve <dgr...@mgh.harvard.edu>:
>> Yes, let's say you have 4 groups (eg, gender and sequence) and one covariate 
>> (BDI score). If you use a DODS model, then you will have 8 regressors (4 
>> intercepts and 4 slopes). To test for an effect of covariate regressing out 
>> the group, then you would have
>> 
>> [0 0  0 0 .25 .25 .25 .25]
>> 
>> The +0.25 computes the mean slope across all groups (note you could also 
>> just use all 1s, you will get the same p-value).
>> 
>> 
>> 
>>> On 03/09/2018 01:43 PM, k.ohmst...@stud.uni-heidelberg.de wrote:
>>> Hi Douglas,
>>> 
>>> thanks for the advice.
>>> 
>>> I have one more question: I want to find correlations of the lGI and the 
>>> respective psychometric measurement, regressing out the effect of gender, 
>>> sequence and the other covariates.
>>> I just had a look at the examples of FSGDs containing two factors with two 
>>> levels each and as far as I understand it, it is only possible to compare 
>>> two of the groups or to find an interaction between groups and covariates.
>>> 
>>> Is it at all possible to find out how the lGI is correlated to one of my 
>>> covariates, i.e. higher values of Beck's Depression Inventory correlate 
>>> with higher/lower values of the lGI, when regressing out the other factors? 
>>> If yes, how do I build the contrast file to do so correctly? I am stuck 
>>> here.
>>> 
>>> Thank you for the time and effort!
>>> 
>>> 
>>> Best regards
>>> 
>>> Kai
>>> 
>>> Zitat von Douglas Greve <dgr...@mgh.harvard.edu>:
>>> 
>>>> Hi Kai, please remember to post to the list. Your FSGD file is not
>>>> quite right. Gender is a discrete variable and should be represented by
>>>> two groups not as a covariate. If Sequence is discrete, then you need
>>>> four groups (Gender by Sequence).
>>>> 
>>>> doug
>>>> 
>>>> 
>>>>> On 3/9/18 3:20 AM, k.ohmst...@stud.uni-heidelberg.de wrote:
>>>>> Dear Douglas,
>>>>> 
>>>>> the fsgd file I used is attached. Thank you for your help!
>>>>> 
>>>>> 
>>>>> Best regards
>>>>> 
>>>>> Kai
>>>>> 
>>>>> Zitat von "Douglas N. Greve" <dgr...@mgh.harvard.edu>:
>>>>> 
>>>>>> can you send your fsgd file so that I have a better idea of what you are
>>>>>> mentioning?
>>>>>> 
>>>>>> 
>>>>>>> On 03/08/2018 08:39 AM, k.ohmst...@stud.uni-heidelberg.de wrote:
>>>>>>> Dear all,
>>>>>>> 
>>>>>>> I am trying to correlate psychometric measurements and the local
>>>>>>> Gyrification Index.
>>>>>>> To do so, I use the FreeSurfer pipeline to calculate the lGI and then
>>>>>>> PALM, following the advice in this thread
>>>>>>> (https://mail.nmr.mgh.harvard.edu/pipermail//freesurfer/2017-March/050703.html).
>>>>>>>  All my subjects are part of the same group, so I used a FSGD with  the
>>>>>>> group "main" to create the design matrix and mask for my data that are
>>>>>>> required by PALM.
>>>>>>> Having a closer look at the design matrix that was created, I found
>>>>>>> that there was a variable for the group that was the same for all my
>>>>>>> patients. As it is the same for all patients, I thought eliminating it
>>>>>>> would not be a problem. But after re-running PALM without it, there
>>>>>>> were huge differences in my results and effects were notably larger
>>>>>>> and more significant.
>>>>>>> 
>>>>>>> Do any of you have any experience which option is best in this case?
>>>>>>> Is it a valid choice to eliminate the variable for the group, as it is
>>>>>>> the same for each patient anyway?
>>>>>>> 
>>>>>>> Furthermore, would you recommend centering for the design matrix? I
>>>>>>> found that this can have an impact, but I am lost on in which cases it
>>>>>>> should be done and in which it shouldn't.
>>>>>>> 
>>>>>>> 
>>>>>>> Thank you for your help!
>>>>>>> 
>>>>>>> 
>>>>>>> Best regards
>>>>>>> 
>>>>>>> Kai Ohmstedt
>>>>>>> 
>>>>>>> 
>>>>>>> _______________________________________________
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>>>>>>> Freesurfer@nmr.mgh.harvard.edu
>>>>>>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>>>>> 
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>>>>>> 
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>>>>> 
>>>>> 
>>> 
>>> 
>>> 
>> 
> 
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