The trouble with highly anisotropic resolutions is that your resolution is
only as good as your worst axis for the convoluted cerebral cortex.  0.8mm
or better would be optimal given a minimum cortical thickness of 1.6mm.

You can always try with what you have and see if it is net beneficial or
not.  

Peace,

Matt.

On 2/28/18, 12:40 PM, "freesurfer-boun...@nmr.mgh.harvard.edu on behalf of
Christopher Markiewicz" <freesurfer-boun...@nmr.mgh.harvard.edu on behalf
of markiew...@stanford.edu> wrote:

>Hi all,
>
>I wonder if people have any data (or anecdotes - I'm not picky) with
>regard to how high of resolution T2w or FLAIR images need to be in order
>to be useful for FreeSurfer's pial refinement. I've seen a couple threads
>suggesting the optimal is ~1mm isotropic, and that thick slice (1x1x5
>mm^3) FLAIR images could be tried, but might hurt more than help, and I'm
>wondering if there's a suboptimal-but-still-useful range somewhere in
>between.
>
>For the record, this isn't a question of what scan parameters are
>recommended, but rather is in the context of data that's already been
>collected, which I would like to preprocess as well as possible.
>
>So, at what resolutions would you recommend (a) completely ignoring
>T2w/FLAIR images; (b) including T2w/FLAIR images that pass QC; (c) trying
>and seeing? Do these answers change at all with T1w resolution?
>
>--
>Chris Markiewicz
>Center for Reproducible Neuroscience
>Stanford University
>
>
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