Hello,

We are attempting to extract cortical thickness values from a pre-defined ROI 
in MNI space.


Originally, we had followed the instructions detailed here:

https://surfer.nmr.mgh.harvard.edu/fswiki/VolumeRoiCorticalThickness

for extraction in MNI space, but now wanted to extract thickness from 
individual subject T1 images in native space.


We attempted to use the same pipeline (e.g. register native space T1 to 
fsaverage) but were unable to get a good registration with several different 
tools.


Is there a better way to do this, either by improving the registration to 
fsaverage, or by transforming the ROI to native space (which we have done) and 
projecting that to a surface/label?


Any suggestions are welcome, and we appreciate the help!


Cheers,


Dan

VolumeRoiCorticalThickness - Free Surfer 
Wiki<https://surfer.nmr.mgh.harvard.edu/fswiki/VolumeRoiCorticalThickness>
surfer.nmr.mgh.harvard.edu
Cortical Thickness of a Volume-defined ROI. This page describes the workflow to 
extract freesurfer cortical thickness values for a region-of-interest (ROI) 
defined in ...



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