which code. I gave 3 options below, which one did you use?

On 11/07/2017 02:43 PM, lanbo Wang wrote:
> I try to use this code to compare left and right hemisphere by paired 
> t-test  and add age as covariate.
>
> Thanks,
> Lanbo
>
> On Tue, Nov 7, 2017 at 11:40 AM, Douglas N Greve 
> <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>> wrote:
>
>     which method are you trying to implement? If #3, then you need to run
>     mris_preproc separately for each subject, and then run that fscalc
>     command
>
>
>     On 11/07/2017 11:33 AM, lanbo Wang wrote:
>     > Hi Douglas,
>     >
>     > Thanks for your reply.
>     > I created the fsgd file as you show me, and run code like this. Am I
>     > right?
>     > 1.
>     > mris_preproc --fsgd Subject.xhemi.dat \
>     >   --target fsaverage_sym --hemi lh \
>     >   --xhemi --paired-diff \
>     >   --srcsurfreg fsaverage_sym.sphere.reg \
>     >   --meas thickness \
>     >   --out lh.lh-rh.thickness.age.sm00.mgh \
>     >  --s subj_02_1  --s subj_04_1  --s subj_05_1  --s subj_06_1  --s
>     > subj_08_1  --s subj_09_1  --s subj_10_1 --s subj_11_1  --s
>     subj_12_1
>     > --s subj_13_1  --s subj_14_1  --s subj_15_1  --s subj_16_1  --s
>     > subj_17_1 --s subj_18_1  --s subj_20_1  --s subj_21_1  --s
>     subj_22_1
>     > --s subj_24_1  --s subj_25_1  --s subj_26_1 --s subj_27_1  --s
>     > subj_29_1  --s subj_32_1
>     >
>     > 2.
>     > mri_glmfit --y lh.lh-rh.thickness.age.sm10.mgh --glmdir
>     > glm.lh.lh-rh.thickness.age.sm10 \
>     > --fsgd Subject.xhemi.dat \
>     > --C Avg-thickness-age-Cor.mtx \
>     > --surf fsaverage_sym lh
>     >
>     > Attachment is fsgd and Avg-thickness-age-cor.mtx.
>     >
>     > All best,
>     > Lanbo Wang
>     >
>     >
>     > On Tue, Nov 7, 2017 at 10:18 AM, Bruce Fischl
>     > <fis...@nmr.mgh.harvard.edu <mailto:fis...@nmr.mgh.harvard.edu>
>     <mailto:fis...@nmr.mgh.harvard.edu
>     <mailto:fis...@nmr.mgh.harvard.edu>>> wrote:
>     >
>     >     Hi Danny
>     >
>     >     you need to give us more information if you want us to help you.
>     >     Please include the command you ran and the entire screen output.
>     >
>     >     cheers
>     >     Bruce
>     >
>     >
>     >     On Tue, 7 Nov 2017, Danny Deng wrote:
>     >
>     >         Dear FDs,
>     >         I encountered an odd situation:
>     >
>     >         My free surfer will always shut down when I run command.
>     >
>     >         My MacOS version is 10.12.6 (16G29) processor: 1.6 GHz Intel
>     >         Core i5
>     >
>     >         I don’t know if the compatibility is fine with my download
>     >         version (MacOS Lion OS X 10.7 (64b
>     >         intel)Stable v6.0.0)
>     >
>     >         Please kindly suggest.
>     >
>     >         Thanks ver much
>     >
>     >         Best Regards,Danny Deng
>     >
>     >
>     >               On Nov 7, 2017, at 7:14 AM, Douglas N Greve
>     >         <gr...@nmr.mgh.harvard.edu
>     <mailto:gr...@nmr.mgh.harvard.edu>
>     <mailto:gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>>>
>     >         wrote:
>     >
>     >
>     >
>     >         On 11/06/2017 12:03 PM, lanbo Wang wrote:
>     >               Dear experts,
>     >
>     >               I have two questions about hemisphere analysis:
>     >
>     >               1) When I run left-right hemisphere paired t-test,
>     can I
>     >         add age as
>     >               covariate? If use fsgd to add covariate, to this
>     paired
>     >         t-test
>     >               analysis, how to make the fsgd table?
>     >
>     >         use this one-group, one-covariate example
>     > https://surfer.nmr.mgh.harvard.edu/fswiki/Fsgdf1G1V
>     <https://surfer.nmr.mgh.harvard.edu/fswiki/Fsgdf1G1V>
>     >         <https://surfer.nmr.mgh.harvard.edu/fswiki/Fsgdf1G1V
>     <https://surfer.nmr.mgh.harvard.edu/fswiki/Fsgdf1G1V>>
>     >               2) I want to reorganize the hemisphere from
>     left-right to
>     >               symptom-nosymptom according to body symptom side
>     record
>     >         and compare
>     >               different between symptom hemisphere and nosymptom
>     >         hemisphere. Can I
>     >               use freesurfer to do it?
>     >
>     >         Yes, though it is a little tricky with multiple ways, each
>     >         complicated
>     >         in its own way.
>     >         1. Create your own design matrix. You can use the one
>     created by
>     >         mri_glmfit to start. Assuming you want
>     >         symptomHemi-nosymptomHemi, then,
>     >         in each subject whose symptomHemi is rh, multiply its
>     line in
>     >         the design
>     >         matrix by -1. Then pass this design matrix to mri_glmfit
>     with --X
>     >         instead of passing an FSGD file.
>     >         2. Load the output of mris_preproc into matlab, eg, y =
>     >         MRIread('y.mgh');, then change the sign as in #1 above, eg,
>     >         y.vol(:,:,:,10) = -y.vol(:,:,:,10); and so on for each
>     applicable
>     >         subject. Then save the data with MRIwrite(y,'new.y.mgh');,
>     >         then run
>     >         mri_glmfit as normal with the new file.
>     >         3. Run mris_preproc for each subject separately to
>     generate an
>     >         lh.lh-rh.thickness.sm00.subject10.mgh file. Then change the
>     >         sign as in
>     >         #1 above with
>     >         fscalc lh.lh-rh.thickness.sm00.subject10.mgh mul -1 -o
>     >         lh.lh-rh.thickness.sm00.subject10.mgh
>     >         Then run mri_concat to concatenate all the subjects together
>     >         in the same
>     >         order as they are listed in the FSGD file, then use this
>     stack
>     >         as input
>     >         the mri_glmfit
>     >
>     >
>     >               Thanks for your patient and help.
>     >
>     >               All best,
>     >               Lanbo Wang
>     >
>     >
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>     >         --
>     >         Douglas N. Greve, Ph.D.
>     >         MGH-NMR Center
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