Hi Douglas,

Thanks for your reply.
I created the fsgd file as you show me, and run code like this. Am I right?
1.
mris_preproc --fsgd Subject.xhemi.dat \
  --target fsaverage_sym --hemi lh \
  --xhemi --paired-diff \
  --srcsurfreg fsaverage_sym.sphere.reg \
  --meas thickness \
  --out lh.lh-rh.thickness.age.sm00.mgh \
 --s subj_02_1  --s subj_04_1  --s subj_05_1  --s subj_06_1  --s subj_08_1
--s subj_09_1  --s subj_10_1  --s subj_11_1  --s subj_12_1  --s subj_13_1
--s subj_14_1  --s subj_15_1  --s subj_16_1  --s subj_17_1  --s subj_18_1
--s subj_20_1  --s subj_21_1  --s subj_22_1  --s subj_24_1  --s subj_25_1
--s subj_26_1  --s subj_27_1  --s subj_29_1  --s subj_32_1

2.
mri_glmfit --y lh.lh-rh.thickness.age.sm10.mgh --glmdir
glm.lh.lh-rh.thickness.age.sm10 \
--fsgd Subject.xhemi.dat \
--C Avg-thickness-age-Cor.mtx \
--surf fsaverage_sym lh

Attachment is fsgd and Avg-thickness-age-cor.mtx.

All best,
Lanbo Wang


On Tue, Nov 7, 2017 at 10:18 AM, Bruce Fischl <fis...@nmr.mgh.harvard.edu>
wrote:

> Hi Danny
>
> you need to give us more information if you want us to help you. Please
> include the command you ran and the entire screen output.
>
> cheers
> Bruce
>
>
> On Tue, 7 Nov 2017, Danny Deng wrote:
>
> Dear FDs,
>> I encountered an odd situation:
>>
>> My free surfer will always shut down when I run command.
>>
>> My MacOS version is 10.12.6 (16G29) processor: 1.6 GHz Intel Core i5
>>
>> I don’t know if the compatibility is fine with my download version (MacOS
>> Lion OS X 10.7 (64b
>> intel)Stable v6.0.0)
>>
>> Please kindly suggest.
>>
>> Thanks ver much
>>
>> Best Regards,Danny Deng
>>
>>
>>       On Nov 7, 2017, at 7:14 AM, Douglas N Greve <
>> gr...@nmr.mgh.harvard.edu> wrote:
>>
>>
>>
>> On 11/06/2017 12:03 PM, lanbo Wang wrote:
>>       Dear experts,
>>
>>       I have two questions about hemisphere analysis:
>>
>>       1) When I run left-right hemisphere paired t-test, can I add age as
>>       covariate? If use fsgd to add covariate, to this paired t-test
>>       analysis, how to make the fsgd table?
>>
>> use this one-group, one-covariate example
>> https://surfer.nmr.mgh.harvard.edu/fswiki/Fsgdf1G1V
>>       2) I want to reorganize the hemisphere from left-right to
>>       symptom-nosymptom according to body symptom side record and compare
>>       different between symptom hemisphere and nosymptom hemisphere. Can I
>>       use freesurfer to do it?
>>
>> Yes, though it is a little tricky with multiple ways, each complicated
>> in its own way.
>> 1. Create your own design matrix. You can use the one created by
>> mri_glmfit to start. Assuming you want symptomHemi-nosymptomHemi, then,
>> in each subject whose symptomHemi is rh, multiply its line in the design
>> matrix by -1. Then pass this design matrix to mri_glmfit with --X
>> instead of passing an FSGD file.
>> 2. Load the output of mris_preproc into matlab, eg, y =
>> MRIread('y.mgh');, then change the sign as in #1 above, eg,
>> y.vol(:,:,:,10) = -y.vol(:,:,:,10); and so on for each applicable
>> subject. Then save the data with MRIwrite(y,'new.y.mgh');, then run
>> mri_glmfit as normal with the new file.
>> 3. Run mris_preproc for each subject separately to generate an
>> lh.lh-rh.thickness.sm00.subject10.mgh file. Then change the sign as in
>> #1 above with
>> fscalc lh.lh-rh.thickness.sm00.subject10.mgh mul -1 -o
>> lh.lh-rh.thickness.sm00.subject10.mgh
>> Then run mri_concat to concatenate all the subjects together in the same
>> order as they are listed in the FSGD file, then use this stack as input
>> the mri_glmfit
>>
>>
>>       Thanks for your patient and help.
>>
>>       All best,
>>       Lanbo Wang
>>
>>
>>       _______________________________________________
>>       Freesurfer mailing list
>>       Freesurfer@nmr.mgh.harvard.edu
>>       https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>
>>
>> --
>> Douglas N. Greve, Ph.D.
>> MGH-NMR Center
>> gr...@nmr.mgh.harvard.edu
>> Phone Number: 617-724-2358
>> Fax: 617-726-7422
>>
>> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
>> FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
>> www.nmr.mgh.harvard.edu/facility/filedrop/index.html
>> Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
>>
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Attachment: Subject.xhemi.dat
Description: Binary data

Attachment: Avg-thickness-age-Cor.mtx
Description: Binary data

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