That four group test will yield the same exact result as

1 -1 0 0

1 0 -1 0

1 0 0 -1

so I think you are ok


On 02/21/2017 03:09 PM, Gold, Andrea (NIH/NIMH) [F] wrote:
>
> Hi,
>
> I am trying to run a cortical thickness analysis comparing four groups 
> – my goal is to conduct an omnibus F-test testing for any group 
> differences. I have 0 covariates/nuisance regressors.
>
> This would be equivalent to the “Contrast 4 group.effect.mtx” in this 
> page, for 3 groups: https://surfer.nmr.mgh.harvard.edu/fswiki/Fsgdf3G0V
>
> But, instead of 3 groups I have 4 groups.
>
> I thought the contrast matrix for 4 groups F-test would be:
>
> 1 -1 0 0
>
> 0 1 -1 0
>
> 0 0 1 -1
>
> But for 3 groups it is:
>
> 1 -1 0
>
> 1 0 -1
>
> Would you please clarify the correct contrast matrix for this test in 
> Freesurfer mri_glmfit?
>
>
> Thank you!
>
> Andrea
>
> -- 
>
> Andrea Gold, Ph.D.
> Section on Development and Affective Neuroscience
>
> National Institute of Mental Health
> 9000 Rockville Pike MSC 2670
> Bldg. 15K
> Bethesda, MD 20892
> Phone: 301-402-6955
> Fax: 301-402-2010
>
> Email: andrea.g...@nih.gov
>
>
>
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-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
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