Hi,

I am trying to run a cortical thickness analysis comparing four groups – my 
goal is to conduct an omnibus F-test testing for any group differences. I have 
0 covariates/nuisance regressors.

This would be equivalent to the “Contrast 4 group.effect.mtx” in this page, for 
3 groups: https://surfer.nmr.mgh.harvard.edu/fswiki/Fsgdf3G0V

But, instead of 3 groups I have 4 groups.

I thought the contrast matrix for 4 groups F-test would be:
1 -1 0 0
0 1 -1 0
0 0 1 -1

But for 3 groups it is:
1 -1 0
1 0 -1


Would you please clarify the correct contrast matrix for this test in 
Freesurfer mri_glmfit?

Thank you!
Andrea

--
Andrea Gold, Ph.D.
Section on Development and Affective Neuroscience
National Institute of Mental Health
9000 Rockville Pike MSC 2670
Bldg. 15K
Bethesda, MD 20892
Phone: 301-402-6955
Fax: 301-402-2010
Email: andrea.g...@nih.gov


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