Hi-

Just gently re-bumping this question/thread.

Noting that the previous thread with recommendations about non-GM ROIs,
which I used in the coming up with the GM list above, is here:
http://www.mail-archive.com/freesurfer@nmr.mgh.harvard.edu/msg50005.html

Thanks,
pt




On Mon, Dec 12, 2016 at 10:43 AM, P Taylor <neon.tay...@gmail.com> wrote:

> And, a minor clarification on one of the ROIs in question--
>
> I should have phrase the comment about ROI #80 as follows:
>  80 non-WM-hypointensities      -------> *should be in list of FS_nongm?
>
> ... since the name clearly implies that it is non-WM.
>
> Basically, I am first wanting to check that the above list of ROIs does
> form the "whole brain" returned by recon-all;  there are a lot more ROIs
> listed in the LUT, of all sorts of tissue types, but it seems like those
> don't often appear in the output.
>
> And following on that, it seems like presently a map of various non-GM
> tissues is made by summing up ROIs of a given type, and then:
> GM_map = whole_brain - WM_map - CSF_map - vent_map.
> However, am I interpreting things correctly that the four ROIs flagged
> above (#30, 62, 80 and 85) seem to be an "other" class that should be
> subtracted away from the whole_brain, as well, such that:
> GM_map = whole_brain - WM_map - CSF_map - vent_map - other_four_regions ?
>
> Thanks,
> pt
>
>
>
> On Mon, Dec 12, 2016 at 1:04 AM, P Taylor <neon.tay...@gmail.com> wrote:
>
>> Hi, Doug-
>>
>>
>> I've looked more into my earlier question of identifying FS-returned
>> regions, in particular:
>> 1) which regions of the whole FreeSurferColorLUT.txt seem to get returned
>> by default recon-all calls (for either the 2000- or 2009-parc+segs); and
>> 2) which of those regions are GM and non-GM (WM/CSF/other), based both on
>> the mri_binarize list you had posted earlier in this thread and on the
>> names given in the LUT.
>>
>> I'd like to pick your brain on this.
>>
>> A) The main questions I have relate to the regions labeled from [0, 256],
>> which seem have the same labelling in both the 2000 and 2009 parc+segs.
>> From a few different FreeSurfer recon-alls on healthy adults, below is a
>> list of the ROIs that seem to be consistently returned by recon-all (a much
>> sparser subset than all 256).
>> For each, I have included the number and label, as well as put arrows by
>> the numbers that, according to the MatchValues list in mri_binarize, should
>> be in either the WM or Vent masks, (and hence non-arrowed regions should be
>> GM, by how that function returns "--gm").
>> My main questions arise about #30, 62, 80 and 85, as they don't appear to
>> be GM-- therefore, am I correct that I should also *exclude* those four
>> regions from a list of GM regions?
>> (Here, "FS_nongm*" means that it was in the list of non-GM regions in
>> mri_binarize, as either unknown, WM, CSF or ventricle.)
>> ------------------------------------------------------------
>> -----------------------------------------
>>   0 Unknown                       -> FS_nongm
>>
>>   2 Left-Cerebral-White-Matter    -> FS_nongm_wm
>>
>>   4 Left-Lateral-Ventricle        -> FS_nongm_vent
>>   5 Left-Inf-Lat-Vent             -> FS_nongm_vent
>>
>>   7 Left-Cerebellum-White-Matter  -> FS_nongm_wm
>>   8 Left-Cerebellum-Cortex
>>
>>  10 Left-Thalamus-Proper
>>  11 Left-Caudate
>>  12 Left-Putamen
>>  13 Left-Pallidum
>>  14 3rd-Ventricle                 -> FS_nongm_vent
>>  15 4th-Ventricle                 -> FS_nongm_vent
>>  16 Brain-Stem
>>  17 Left-Hippocampus
>>  18 Left-Amygdala
>>
>>  24 CSF                           -> FS_nongm_csf
>>
>>  26 Left-Accumbens-area
>>
>>  28 Left-VentralDC
>>
>>  30 Left-vessel                 -------> *should be in list of FS_nongm?
>>  31 Left-choroid-plexus           -> FS_nongm_vent
>>
>>  41 Right-Cerebral-White-Matter   -> FS_nongm_wm
>>
>>  43 Right-Lateral-Ventricle       -> FS_nongm_vent
>>  44 Right-Inf-Lat-Vent            -> FS_nongm_vent
>>
>>  46 Right-Cerebellum-White-Matter -> FS_nongm_wm
>>  47 Right-Cerebellum-Cortex
>>
>>  49 Right-Thalamus-Proper
>>  50 Right-Caudate
>>
>>  52 Right-Pallidum
>>  53 Right-Hippocampus
>>  54 Right-Amygdala
>>
>>  58 Right-Accumbens-area
>>
>>  60 Right-VentralDC
>>
>>  62 Right-vessel                -------> *should be in list of FS_nongm?
>>  63 Right-choroid-plexus          -> FS_nongm_vent
>>
>>  72 5th-Ventricle                 -> FS_nongm_vent
>>
>>  77 WM-hypointensities            -> FS_nongm_wm
>>
>>  80 non-WM-hypointensities      -------> *should be in list of
>> FS_nongm_wm?
>>
>>  85 Optic-Chiasm                -------> *should be in list of FS_nongm?
>>
>> 251 CC_Posterior                  -> FS_nongm_wm
>> 252 CC_Mid_Posterior              -> FS_nongm_wm
>> 253 CC_Central                    -> FS_nongm_wm
>> 254 CC_Mid_Anterior               -> FS_nongm_wm
>> 255 CC_Anterior                   -> FS_nongm_wm
>> ------------------------------------------------------------
>> --------------------
>>
>> It seem that the new version of mri_binarize that you had sent me might
>> still include those four flagged regions in the 'mri_binarize --gm' output.
>>
>>
>> B) For the ROIs specific to the 2000aparc+aseg, I think it also seems
>> pretty clear:
>> + 1000 and 2000 are returned as "ctx_*_unknown";
>> + All ROIs in the intervals [1001, 1003] and [1005, 1035] can be
>> returned, and these are all LH GM;
>> + All ROIs in the intervals [2001, 2003] and [2005, 2035] can be
>> returned, and these are all RH GM;
>> + ROIs '1004' and '2004' are the "ctx-?h-corpuscallosum", which would be
>> WM, but they don't seem to be returned.
>>
>>
>> C) For the ROIs specific to 2009aparc+aseg, I think it also seems pretty
>> clear:
>> + 11100 and 12100 are returned as "ctx_*_Unknown";
>> + All ROIs in the intervals [11101, 11141] and [11143, 11175] can be
>> returned, and these are all LH GM;
>> + All ROIs in the intervals [12101, 12141] and [12143, 12175] can be
>> returned, and these are all RH GM;
>> + ROIs '11142' and '12142' are the "ctx_?h_Medial_wall", which would be
>> non-GM, but they don't seem to be returned.
>>
>>
>> D) And you mentioned that the regions in the interval [3000, 4035] are WM
>> parcellations.
>>
>>
>> So, in total, does that seem like a complete categorization of regions
>> that are typically returned, as well as their classification as either GM
>> or non-GM?  And in particular, I would be happy to know your thoughts on
>> the flagged ROIs in the interval [0, 256].
>>
>>
>> Thanks,
>> pt
>>
>
>
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