Thank you Jurgen! That helps a lot. Good to know that the results are not driven by any difference in varience.
Thanks all, Eelco 2016-10-13 12:00 GMT-03:00 Juergen Haenggi <j.haen...@psychologie.uzh.ch>: > Dear Eelco > > years ago i posed a similar question on the FS email list > > https://mail.nmr.mgh.harvard.edu/pipermail//freesurfer/ > 2011-November/021386.html > > a part of the response is below > > >>>* The other question is how mri_glmfit estimates the variance. Because I > >>>have > *>>>* only one subject in the patient group, there is not variance in that > group > *>>>* and therefore I guess mri_glmfit used pooled (across both groups) > estimates > *>>>* of variance, isn't it? > *>>> >>> >>* Yes, it uses pooled estimates. > *>>>>* doug* > > if you are concerned with respect to the variance estimates, it does not > matter because variance is estimated pooledly, i.e. across both groups. > hope this helps > > Cheers > Jürgen > > ------------------------------------------------------------ > ----------------------------------------- > University of Zurich > Dr. Jürgen Hänggi, Ph.D. > Department of Psychology > Division Neuropsychology > Binzmuehlestrasse 14, PO Box 25 > 8050 Zurich, Switzerland > > 0041 44 635 73 97 (phone office) > 0041 76 445 86 84 (phone mobile) > 0041 44 635 74 09 (fax office) > BIN 4.D.04 (office room number) > > j.haen...@psychologie.uzh.ch (email) > http://www.psychologie.uzh.ch/neuropsy/ (website) > http://www.juergenhaenggi.ch (private website) > > This e-mail (and any attachment/s) contains confidential and/or privileged > information. If you are not the intended recipient (or have received this > e-mail in error) please notify the sender immediately and destroy this > e-mail. Any unauthorised copying, disclosure or distribution of the > material in this e-mail is strictly forbidden. > ------------------------------------------------------------ > ----------------------------------------- > > > > > Am 13.10.2016 um 15:56 schrieb Eelco van Duinkerken: > > Hi all, > > I am using FS with data from 2 different studies that were acquired on the > same MRI-machine with the same T1 and FLAIR sequences. Unfortunately, the > group sizes are not very balanced, with 31 controls, 16 obese and 32 > diabetes patients. > > Is the GLM for thickness used in FS very sensitive to this unequal group > size? > > > Thanks for the help, > > Eelco > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > > The information in this e-mail is intended only for the person to whom it > is > addressed. If you believe this e-mail was sent to you in error and the > e-mail > contains patient information, please contact the Partners Compliance > HelpLine at > http://www.partners.org/complianceline . If the e-mail was sent to you in > error > but does not contain patient information, please contact the sender and > properly > dispose of the e-mail. > > > > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > > The information in this e-mail is intended only for the person to whom it > is > addressed. If you believe this e-mail was sent to you in error and the > e-mail > contains patient information, please contact the Partners Compliance > HelpLine at > http://www.partners.org/complianceline . If the e-mail was sent to you in > error > but does not contain patient information, please contact the sender and > properly > dispose of the e-mail. > > -- Eelco van Duinkerken, PhD Pontifícia Universidade Católica | Department of Psychology | R. Marquês de São Vicente 225 | Gávea, Rio de Janeiro - RJ | CEP 22451-900 | Brasil | E-mail: e.vanduinker...@vumc.nl | Phone: +55-21-35271855 | http://lattes.cnpq.br/7180895567820901 & VU University Medical Center | Department of Medical Psychology | De Boelelaan 1117 | 1081 HV | Amsterdam | The Netherlands
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