Hi Eelco
it depends on how you setup your GLM. Are you trying to regress out the
effects of obesity in some way? If you give us more details I expect
someone else can answer your question (Doug!)
cheers
Bruce
On Thu, 13 Oct 2016, Eelco van Duinkerken
wrote:
Thanks for the quick reply!
So if I understand correctly, the power of say the controls vs. diabetes
(indeed it is type 2 diabetes) comparison is constrained by the sample size
of the obese group?
2016-10-13 11:02 GMT-03:00 Bruce Fischl <fis...@nmr.mgh.harvard.edu>:
Hi Eelco
it isn't really a question of whether our implementation is
senstitive to
this. It's that in general your power will be constrained by the
size of
the smaller group (I assume this is Type 2 diabetes by the way).
cheers
Bruce
On Thu, 13 Oct 2016, Eelco van Duinkerken wrote:
> Hi all,
> I am using FS with data from 2 different studies that were
acquired on the
> same MRI-machine with the same T1 and FLAIR sequences.
Unfortunately, the
> group sizes are not very balanced, with 31 controls, 16 obese
and 32
> diabetes patients.
>
> Is the GLM for thickness used in FS very sensitive to this
unequal group
> size?
>
>
> Thanks for the help,
>
> Eelco
>
>
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Eelco van Duinkerken, PhD
Pontifícia Universidade Católica | Department of Psychology |
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Brasil |
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