Thanks Dr. Harms and Dr. Greve. So can I do the cortical thickness comparison if we have healthy controls data from the same scanner but acquired using different protocol e.g. if we get access of age-matched healthy controls data from another lab who used the same scanner?
Thanks. On Fri, Sep 30, 2016 at 12:02 PM, Douglas N Greve <gr...@nmr.mgh.harvard.edu > wrote: > You can do the comparison, but the interpretation is difficult. If you > see a difference, how do you know it is not due to the scanner? There's > not much you can do ... > > > On 09/29/2016 02:54 PM, Martin Juneja wrote: > > Hello FS experts, > > > > I have a data set of 20 subjects (patients) collected at location-1 > > with 3T Siemens scanner. Also, I have a set of age-matched 20 subjects > > (controls) collected at location-2 with 3T Siemens scanner. > > > > I am interested in comparing cortical thickness between controls and > > patients using FreeSurfer but I am not sure if I can do that since I > > have both the data sets collected at two different locations. > > > > I would really appreciate any inputs on this. > > > > I tried to find some papers on scanner differences but all I could > > find was between 1.5 T vs 3T or 3T vs 7T. Is there any special > > covariates I need to define for this purpose (if so then at which step > > during analysis?) or is it not possible at all? > > > > Thanks. > > > > > > _______________________________________________ > > Freesurfer mailing list > > Freesurfer@nmr.mgh.harvard.edu > > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > -- > Douglas N. Greve, Ph.D. > MGH-NMR Center > gr...@nmr.mgh.harvard.edu > Phone Number: 617-724-2358 > Fax: 617-726-7422 > > Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting > FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2 > www.nmr.mgh.harvard.edu/facility/filedrop/index.html > Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/ > > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > > The information in this e-mail is intended only for the person to whom it > is > addressed. If you believe this e-mail was sent to you in error and the > e-mail > contains patient information, please contact the Partners Compliance > HelpLine at > http://www.partners.org/complianceline . If the e-mail was sent to you in > error > but does not contain patient information, please contact the sender and > properly > dispose of the e-mail. > >
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