yup, that is a reasonable approach
Bruce
On Mon, 4 Jul 2016, Harms, Michael
wrote:
Hi,
Why not use total surface area to control for analyses involving area, and
mean cortical thickness to control for thickness? I’ve posted to the list
before regarding this, so you should be able to find those posts.
cheers,
-MH
--
Michael Harms, Ph.D.
-----------------------------------------------------------
Conte Center for the Neuroscience of Mental Disorders
Washington University School of Medicine
Department of Psychiatry, Box 8134
660 South Euclid Ave.Tel: 314-747-6173
St. Louis, MO 63110Email: mha...@wustl.edu
On 7/4/16, 9:12 AM, "freesurfer-boun...@nmr.mgh.harvard.edu on behalf of
Clara Kühn" <freesurfer-boun...@nmr.mgh.harvard.edu on behalf of
cku...@cbs.mpg.de> wrote:
Do you know, if there are any publications concerning this matter? So far
I've found only this
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0148852
that controls for tGM only for area and not CT.
Cheers Clara
----- Ursprüngliche Mail -----
Von: "Bruce Fischl" <fis...@nmr.mgh.harvard.edu>
An: "Freesurfer support list" <freesurfer@nmr.mgh.harvard.edu>
Gesendet: Montag, 4. Juli 2016 15:37:57
Betreff: Re: [Freesurfer] controlling for total gray matter volume
sounds right to me
Bruce
On Mon, 4 Jul 2016, Clara Kühn wrote:
I have decided now to not control for ICV or total gray matter volume
when looking at cortical thickness but to control for total gray matter
volume when looking at surface area. Does that sound about right?
Cheers, Clara
----- Ursprüngliche Mail -----
Von: "Arkadiy Maksimovskiy" <arkad...@bu.edu>
An: freesurfer@nmr.mgh.harvard.edu
Gesendet: Samstag, 2. Juli 2016 18:36:51
Betreff: Re: [Freesurfer] controlling for total gray matter volume
Hi Clara,
If I am understanding your question correctly, you don't need to control
for brain volume when looking at thickness analyses.
See quote below from this link:
http://www.freesurfer.net/fswiki/eTIV
"Note that this correction is only useful in situations where the
structure scales with head size. Outside of this, correction just adds
noise, or provides inaccurate data. In the case of the measures from
Freesurfer, one would apply correction to the volume measures and not
thickness measures. This is because volume scales with head size which is
mostly due to changes in surface area, whereas thickness alone scales to
a much less degree."
Best,
Arkadiy
On Sat, Jul 2, 2016 at 12:00 PM, <
freesurfer-requ...@nmr.mgh.harvard.edu > wrote:
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Today's Topics:
1. controlling for total gray matter volume (Clara K?hn)
2. cotrolling for total gray matter volume (Clara K?hn)
----------------------------------------------------------------------
Message: 1
Date: Thu, 30 Jun 2016 15:19:43 +0200 (CEST)
From: Clara K?hn < cku...@cbs.mpg.de >
Subject: [Freesurfer] controlling for total gray matter volume
To: Freesurfer support list < freesurfer@nmr.mgh.harvard.edu >
Message-ID:
< 600644700.119350.1467292783757.javamail.zim...@cbs.mpg.de >
Content-Type: text/plain; charset=utf-8
Dear FreeSurfer experts,
I would like to look at longitudinal thickness data and want to control
for total gray matter volume. Should I use that information from the
CROSS before anything has been registered and smoothed or from the LONG
after they have been registered to the BASE?
Also I was wondering if it is useful to control for total gray matter
volume when looking at surface area?
Thanks for your help!
Clara
------------------------------
Message: 2
Date: Thu, 30 Jun 2016 15:01:06 +0200 (CEST)
From: Clara K?hn < cku...@cbs.mpg.de >
Subject: [Freesurfer] cotrolling for total gray matter volume
To: Freesurfer support list < freesurfer@nmr.mgh.harvard.edu >
Message-ID:
< 1473114832.117985.1467291666701.javamail.zim...@cbs.mpg.de >
Content-Type: text/plain; charset=utf-8
Dear FreeSurfer experts,
I would like to look at longitudinal thickness data and want to control
for total gray matter volume. Should I use that information from the
CROSS before anything has been registered and smoothed or from the LONG
after they have been registered to the BASE?
Also I was wondering if it is useful to control for total gray matter
volume when looking at surface area?
Thanks for your help!
Clara
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