Hi Kasper,

short answer: yes.

long answer
1. yes
2. yes (you need to create a table in cross sectional format (no fsid-base column) and the fsid needs to be the tp.long.base names for baseline visit. the path should point to where these *.long.* directories are located).
2. yes (fsaverage should be linked there anyway, right?)
3. yes

;-) Martin

On 03/09/2016 03:42 PM, Kasper Jessen wrote:
Dear FreeSurfer experts,

We have a longitudinal study design with up to 5 time points. However, we both want to do a baseline cross-sectional analysis and later a longitudinal analysis. All subjects have been run through the longitudinal pipeline (only the base was edited). We want to start analysing baseline cross-sectionally using QDEC. I have read through the wiki guides but would like to make sure that we are doing it correctly. We have done/plan to do the following:

1. The [CROSS], edited [BASE] and [LONG] is processed.

2. We will create a qdec table called qdec.table.dat. However, because we want to use the improved longitudinal runs [LONG] (i.e., because the [BASE] has been edited] the first column in the QDEC table (i.e., fsid) has been changed to include the longitudinal names (please see below). In addition, we have included the line /SUBJECTS_DIR /my/path/to/subject/data/ to let FreeSurfer know that it is the longitudinal directories that should be used (is this the correct why to let FreeSurfer know that it is the "longitudinal runs" which should be used?).

SUBJECTS_DIR /my/path/to/subject/data
fsid Gender Group Age
d115a.long.d115_base 1 1 19
d120a.long.d120_base 0 1 22
...

2. We transfer the default fsaverage to the subject directory.
3. To presmooth the data onto the target we run the following command: *recon-all -long <tpid> <baseid> -qcache*
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When the above steps are done we plan to load it into QDEC.
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Is the above steps correct for doing a cross-sectional group analysis in QDEC?

Best regards,
Kasper Jessen
MD, PhD student
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--
Martin Reuter, PhD
Assistant Professor of Radiology, Harvard Medical School
Assistant Professor of Neurology, Harvard Medical School
A.A.Martinos Center for Biomedical Imaging
Massachusetts General Hospital
Research Affiliate, CSAIL, MIT
Phone: +1-617-724-5652
Web  : http://reuter.mit.edu

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