I would say that you can do that only if your data is continous (preferably close to normally distributed).
Binary data or any non-continous data requires a different approach (eg. Generalized Estimating Equations). Best-Jorge De: Martin Reuter <mreu...@nmr.mgh.harvard.edu> Para: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu> Enviado: Martes 29 de septiembre de 2015 9:04 Asunto: Re: [Freesurfer] LME toolbox for longitudinal FA volume maps ? Hi Matthieu, if all your images are perfectly registered, you can do LME on a voxel-by-voxel basis, just as if you had hippocampal volume or any other ROI measure. Best, Martin On 09/29/2015 06:46 AM, Matthieu Vanhoutte wrote: Dear experts, I would like to know if it is possible to make a longitudinal study with LME toolbox from volume FA maps registered in a common space ? I don't have T1 images so the recon-all process couldn't be processed. But if I put my 3D FA volume of dim = [nx,ny,nz] in a 1D nx*ny*nz voxels format, could it be in good way for LME ? Thanks for helping ! Best regards, Matthieu _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer -- Martin Reuter, PhD Assistant Professor of Radiology, Harvard Medical School Assistant Professor of Neurology, Harvard Medical School A.A.Martinos Center for Biomedical Imaging Massachusetts General Hospital Research Affiliate, CSAIL, MIT Phone: +1-617-724-5652 Web : http://reuter.mit.edu _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
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