Dear freesufers, I quick question about smoothing of data in cortical thickness analysis. I have a comparison that is rather borderline significant. When using smoothing of 10 mm I get a limited region in the frontal lobe that is differs between groups. Changing to 15 mm I get larger regions - and also some parts of the temporal lobe differs in the comparison.
The 15 mm smoothing provides results that are more consistent with the hypothesis - however I do not know if this amount of smoothing overestimate the difference between groups? Eric
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