so the GM is properly labeled by the aseg there? What about the faint wm?
On 
Tue, 25 Nov 2014, Octavian Lie wrote:

> Dear Bruce,
> 
> I am not sure how an ok aseg.mgz would look like for a lesion like that, but
> it looks like it includes one larger gyrus excluded by the pia, see
> attached, I would be happy to retrieve that one as it is the bulkiest of all
> the ones left out.
> Thank you,
> 
> Octavian
> 
> On Tue, Nov 25, 2014 at 7:38 AM, Bruce Fischl <fis...@nmr.mgh.harvard.edu>
> wrote:
>       Hi Octavian
>
>       I wouldn't use control points since it really isn't healthy wm.
>       The only
>       thing you can do is edit the wm.mgz and possibly also the
>       brainmask, but
>       it's so abnormal looking you may not be able to get accurate
>       surfaces.
>       How does the aseg look? If it is ok there may be one other
>       option.
>
>       cheers
>       Bruce
> 
>
>       On Tue, 25 Nov 2014, Octavian Lie wrote:
>
>       > Dear All,
>       > any suggestion about this type of problem? I tried control
>       points through
>       > the middle/axis of the atrophic gyri (intensity 30-90 in T1 or
>       brainmask),
>       > wm.mgz edits through the same (adding from brainmask by
>       cloning those
>       > voxels; painting 110; or 255 brush), and modifying brainmask
>       directly by
>       > painting 110 internsity voxels through the same (gyri
>       interiors, where wm is
>       > supposed to be). Did not work, the atrophic gyri continue to
>       remain outside
>       > the pia. Again, this is an example of an eccentric lesion with
>       gyral
>       > atrophy, without interruption in the gray matter ribbon but
>       very faint wm
>       > signal through the base of the affected gyri.
>       > Thanks,
>       > Octavian
>       >
>       >
>       >
>       > ---------- Forwarded message ----------
>       > From: Octavian Lie <octavian....@gmail.com>
>       > Date: Tue, Nov 18, 2014 at 10:50 AM
>       > Subject: Eccentric lesions
>       > To: "freesurfer@nmr.mgh.harvard.edu"
>       <freesurfer@nmr.mgh.harvard.edu>
>       >
>       >
>       > Dear All,
>       >
>       > I am interested at getting as good pial/cortical
>       reconstructions as possible
>       > on a series of epilepsy pt scans, some showing eccentric
>       (cortical) lesions
>       > (focal encephalomalacias, infarcts, or after focal
>       resections). One
>       > particularly difficult lesion type to get an accurate cortical
>       surface is
>       > where there are prongs of grey matter bulging out (like a bag
>       of worms),
>       > (mostly) without visible wm, see attached picture. These
>       prongs are
>       > maintained in the brainmask.mgz and brain.finalsurfs.mgz, but
>       not included
>       > in the pia with the default recon. Lesion voxel intensities
>       vary from 30-90.
>       > I tried cp, wm edits (using brainmask or T1 as referece),
>       both, did not
>       > matter, it did not work.
>       >
>       > Since I am not intested in wm/subcortical segmentation but
>       just in a good
>       > pia, I was wondering if I 'create' thin wm tracts through the
>       center of
>       > these gm prongs to help pial segmentation. If this is a valid
>       option, should
>       > I create those in brainmask, brain.finalsurfs or wm.mgz, and
>       should I use
>       > 110 or 255 for the brush?
>       > Any other suggestions are appreciated. Nevertheless, I know
>       there is a lot
>       > of tweaking of each lesion, and I try for more of a global
>       approach to these
>       > kinds of lesions.
>       >
>       > Thank you,
>       >
>       > Octavian.
>       >
>       >
>       >
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