Doug and Bruce.
Many thousands of thanks

Mohamad
________________________________________
From: freesurfer-boun...@nmr.mgh.harvard.edu 
[freesurfer-boun...@nmr.mgh.harvard.edu] on behalf of Douglas N Greve 
[gr...@nmr.mgh.harvard.edu]
Sent: Thursday, November 06, 2014 12:12 PM
To: freesurfer@nmr.mgh.harvard.edu
Subject: Re: [Freesurfer] White matter volume

On 11/06/2014 12:53 AM, Alshikho, Mohamad J. wrote:
>
> Dear Bruce,
>
> My questions is just to learn and to improve my understanding.
>
> The commands recon-all and dt-recon are routinely generating the
> statistics  at the end of there running and we can check the results
> in aseg.stats (the output of recon-all) and fa.stats (the output of
> dt-recon for FA).
>
> In those files we have the white matter volume for many different
> parts of the brain like the right and left cerebral white matter.
>
> If we check the volumes in those files we can see that we have
> differences between the numbers and I can explain that by the
> following: in aseg.stats the white matter volume is derived from the
> T1 segmentation in the structural space and in fa.stats the white
> matter volume is derived from the FA map in diffusion space and the
> difference between the volumes is the difference between the accuracy
> of the images in different spaces.
>
Almost. The value in aseg.stats is derived from the surfaces which is
even more accurate than the 1mm space values (though they are pretty close).
>
> Now:
>
> 1. If we want to study the relationship between the FA and the right
> hemispheric white matter volume for example, we should not care about
> the volumes in fa.stasts  because it is not accurate?!
>
I would use the value from the aseg.stats file. I would not say that the
value from fa.stats is not accurate, it is just not as accurate as the
surface-based measure.
>
> in this case what is the optimal and correct method in freeSurfer to
> do such like this comparison, is it by moving the FA map to the
> structural space by registering the FA map to T1  or by using the
> volumes in aseg.stats and the metrics values from fa.stats? or we can
> use the fa values and the volumes from fa.stats?
>
Use the value from the aseg.stats
>
> 2.What is the exact usage for the volumes mentioned in FA.stats
>
They may or may not be used for anything. They are just values that are
recorded by the program.
>
> 3. What is the meaning and the exact usage of min-max intensity range
> (intensity of what) in aseg.stats and fa.stats
>
The min is the minimum value of the intensity (norm.mgz or fa.nii) in
the ROI, max is the maximum. Again, they may or may not be used for
anything. They are just values that are recorded by the program.

doug
>
>
> So Sorry for this long email but as always I am looking forward to
> learn from you
>
> Thanks
>
>
> Mohamad
>
>
>
>
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> Freesurfer@nmr.mgh.harvard.edu
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--
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

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