Dear Freesurfer Users,

I am trying different LME models to describe the time evolution of cortical 
thickness in anorexia patients. The LME tools provide a function (lme_mass_LR) 
to test whether a model with q+1 random effects is better (fits the data 
better) than one with q random effects, eg whether a model with random 
intercept and slope is better than one with only intercept random.

I have two questions:
1- is there a similar function to test whether the model with intercept as a 
random effect is better than the model with slope as a random effect (ie two 
models with the same number of random effects)? In another thread I read one 
should judge which random effect is to be chosen from the percentage of voxels 
where one has convergence. It sounds reasonable, but an explanation of why this 
should be so would be welcome.
2- does it make sense to use lme_mass_LR to test whether a model with 1 random 
effect is better than one with 0 random effects? I have it with something like:

LR_pval = lme_mass_LR(lhstats_0RE,lhstats_1RE,0);

And I get as a result LR_pval= 0.3 (a constant vector) which I do not know how 
to interpret: something wrong, this test does not make any sense, choose the 0 
random effect model ...

Thanks in advance for your help.

Cheers,
Fabio


Dr. Fabio Bernardoni
wiss. Mitarbeiter
Klinik und Poliklinik für Kinder- und Jugendpsychiatrie und -psychotherapie

Tel. +49 (0)351 458-5245
Fax +49 (0)351 458-7206

Universitätsklinikum Carl Gustav Carus
an der Technischen Universität Dresden
Anstalt des öffentlichen Rechts des Freistaates Sachsen
Fetscherstraße 74, 01307 Dresden
http://www.uniklinikum-dresden.de

Vorstand: Prof. Dr. med. D. M. Albrecht (Sprecher), Wilfried E. B. Winzer
Vorsitzender des Aufsichtsrates: Prof. Dr. med. Peter C. Scriba
USt.-IDNr.: DE 140 135 217, St.-Nr.: 203 145 03113
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