Hi Doug,

Thank you for your reply. By precomputed do you mean the FDR in the GUI?
Apologies I'm still new to the program!

I am planning on running an ROI analysis so will need to run it for that
anyway (I think?)

Best,

Jackie


On 24 April 2014 21:47, Douglas N Greve <gr...@nmr.mgh.harvard.edu> wrote:

>
> First of all, do you really need to run the simulation? If you are just
> doing a whole hemisphere analysis on fsaverage, then you can use the
> precomputed option.
>
> doug
>
> On 04/24/2014 02:20 PM, Jacqueline Elaine Fitzgerald wrote:
> > Hi,
> >
> > I am having problem when running the Monte Carlo script. The script
> > seems to fail after only a few simulations but it does not give me any
> > error message, it just says 'killed'. I am running it on 126
> > participants (2 groups of 63) and I have tried it on a number of
> > different measures (sulc, area etc.). I thought it may be an space
> > issue but I cleared all other files but that did not seem to make any
> > difference.
> >
> > This is what is printed out on the terminal:
> >
> > [fitzgeje@lonsdale01 qdec]$ mri_glmfit-sim --glmdir Rh_JacobianW_15
> > --sim mc-z 10000 1.3 mc-z.negative --sim-sign neg --overwrite
> >
> > cmdline mri_glmfit --y
> > /projects/pi-lgallagh/HPC_12_00408/qdec/Rh_JacobianW_15/y.mgh --fsgd
> > /projects/pi-lgallagh/HPC_12_00408/qdec/Rh_JacobianW_15/qdec.fsgd dods
> > --glmdir /projects/pi-lgallagh/HPC_12_00408/qdec/Rh_JacobianW_15
> > --surf fsaverage rh --label
> > /projects/pi-lgallagh/HPC_12_00408/fsaverage/label/rh.cortex.label --C
> >
> /projects/pi-lgallagh/HPC_12_00408/qdec/Rh_JacobianW_15/contrasts/rh-Avg-Intercept-jacobian_white.mat
> > --C
> >
> /projects/pi-lgallagh/HPC_12_00408/qdec/Rh_JacobianW_15/contrasts/rh-Diff-ASD-CTRL-Intercept-jacobian_white.mat
> >
> >
> >
> > WARNING: unrecognized mri_glmfit cmd option dods
> >
> >
> > SURFACE: fsaverage rh
> >
> > /home/support/apps/apps/freesurfer/4.5.0/bin/mri_glmfit-sim
> >
> > --glmdir Rh_JacobianW_15 --sim mc-z 10000 1.3 mc-z.negative --sim-sign
> > neg --overwrite
> >
> > $Id: mri_glmfit-sim,v 1.1.2.20 2009/07/16 16:36:47 greve Exp $
> >
> > Thu Apr 24 18:58:31 IST 2014
> >
> > Linux lonsdale01.cluster 2.6.32-358.23.2.el6.x86_64 #1 SMP Wed Oct 16
> > 11:13:47 CDT 2013 x86_64 x86_64 x86_64 GNU/Linux
> >
> > fitzgeje
> >
> > setenv SUBJECTS_DIR /projects/pi-lgallagh/HPC_12_00408/
> >
> > FREESURFER_HOME /home/support/apps/apps/freesurfer/4.5.0
> >
> > DoPoll = 0
> >
> > DoPBSubmit = 0
> >
> > DoBackground = 0
> >
> > DiagCluster = 0
> >
> > gd2mtx = dods
> >
> > fwhm = 21.770250
> >
> > nSimPerJob = 10000
> >
> > 1/1 Thu Apr 24 18:58:31 IST 2014
> >
> > mri_glmfit --y
> > /projects/pi-lgallagh/HPC_12_00408/qdec/Rh_JacobianW_15/y.mgh --C
> >
> Rh_JacobianW_15/tmp.mri_glmfit-sim-21064/rh-Avg-Intercept-jacobian_white.mtx
> > --C
> >
> Rh_JacobianW_15/tmp.mri_glmfit-sim-21064/rh-Diff-ASD-CTRL-Intercept-jacobian_white.mtx
> > --mask Rh_JacobianW_15/mask.mgh --sim mc-z 10000 1.3
> > Rh_JacobianW_15/csd/mc-z.negative.j001 --sim-sign neg --fwhm 21.770250
> > --fsgd Rh_JacobianW_15/y.fsgd dods --label
> > /projects/pi-lgallagh/HPC_12_00408/fsaverage/label/rh.cortex.label
> > --surf fsaverage rh white
> >
> > INFO: ignoring tag Creator
> >
> > INFO: ignoring tag SUBJECTS_DIR
> >
> > INFO: ignoring tag SynthSeed
> >
> > reading group avg surface area 822 cm^2 from file
> >
> > Reading in average area
> > /projects/pi-lgallagh/HPC_12_00408//fsaverage/surf/rh.white.avg.area.mgh
> >
> > reading group avg surface area 822 cm^2 from file
> >
> > Reading in average area
> > /projects/pi-lgallagh/HPC_12_00408//fsaverage/surf/rh.white.avg.area.mgh
> >
> > simbase Rh_JacobianW_15/csd/mc-z.negative.j001
> >
> > gdfReadHeader: reading Rh_JacobianW_15/y.fsgd
> >
> > INFO: demeaning continous variables
> >
> > Continuous Variable Means (all subjects)
> >
> > Class Means of each Continuous Variable
> >
> > 1 groupASD
> >
> > 2 groupCTRL
> >
> > INFO: gd2mtx_method is dods
> >
> > Reading source surface
> > /projects/pi-lgallagh/HPC_12_00408//fsaverage/surf/rh.white
> >
> > Number of vertices 163842
> >
> > Number of faces    327680
> >
> > Total area         65020.765625
> >
> > AvgVtxArea       0.396850
> >
> > AvgVtxDist       0.717994
> >
> > StdVtxDist       0.193566
> >
> > INFO: fwhm2niters: NOT fixing group surface area
> >
> > Surface smoothing by fwhm=21.770250, niters=441.000000
> >
> >
> > $Id: mri_glmfit.c,v 1.138.2.15 2009/07/27 17:43:10 greve Exp $
> >
> > cwd /projects/pi-lgallagh/HPC_12_00408/qdec
> >
> > cmdline mri_glmfit --y
> > /projects/pi-lgallagh/HPC_12_00408/qdec/Rh_JacobianW_15/y.mgh --C
> >
> Rh_JacobianW_15/tmp.mri_glmfit-sim-21064/rh-Avg-Intercept-jacobian_white.mtx
> > --C
> >
> Rh_JacobianW_15/tmp.mri_glmfit-sim-21064/rh-Diff-ASD-CTRL-Intercept-jacobian_white.mtx
> > --mask Rh_JacobianW_15/mask.mgh --sim mc-z 10000 1.3
> > Rh_JacobianW_15/csd/mc-z.negative.j001 --sim-sign neg --fwhm 21.770250
> > --fsgd Rh_JacobianW_15/y.fsgd dods --label
> > /projects/pi-lgallagh/HPC_12_00408/fsaverage/label/rh.cortex.label
> > --surf fsaverage rh white
> >
> > sysname  Linux
> >
> > hostname lonsdale01.cluster
> >
> > machine  x86_64
> >
> > user     fitzgeje
> >
> > FixVertexAreaFlag = 1
> >
> > UseMaskWithSmoothing     1
> >
> > fwhm     21.770250
> >
> > niters    441.000000
> >
> > OneSampleGroupMean 0
> >
> > y  /projects/pi-lgallagh/HPC_12_00408/qdec/Rh_JacobianW_15/y.mgh
> >
> > logyflag 0
> >
> > usedti  0
> >
> > FSGD Rh_JacobianW_15/y.fsgd
> >
> > labelmask
> >  /projects/pi-lgallagh/HPC_12_00408/fsaverage/label/rh.cortex.label
> >
> > mask Rh_JacobianW_15/mask.mgh
> >
> > maskinv 0
> >
> > glmdir (null)
> >
> > IllCondOK 0
> >
> > DoFFx 0
> >
> > Loading y from
> > /projects/pi-lgallagh/HPC_12_00408/qdec/Rh_JacobianW_15/y.mgh
> >
> > INFO: gd2mtx_method is dods
> >
> > Matrix condition is 1
> >
> > /projects/pi-lgallagh/HPC_12_00408/fsaverage/label/rh.cortex.label
> > /projects/pi-lgallagh/HPC_12_00408/fsaverage/label/rh.cortex.label
> >
> > Found 149926 points in label.
> >
> > Found 149926 voxels in mask
> >
> > search space = 75188.6
> >
> > DOF = 124
> >
> > thresh = 1.3, threshadj = 0.99897
> >
> >
> >
> > Starting simulation sim over 10000 trials
> >
> > Smoothing done, nsteps = 441, tsec = 69.733
> >
> > Smoothing done, nsteps = 441, tsec = 69.799
> >
> > Smoothing done, nsteps = 441, tsec = 69.754
> >
> > Smoothing done, nsteps = 441, tsec = 69.749
> >
> > Smoothing done, nsteps = 441, tsec = 69.743
> >
> > Smoothing done, nsteps = 441, tsec = 69.749
> >
> > Smoothing done, nsteps = 441, tsec = 69.737
> >
> > Smoothing done, nsteps = 441, tsec = 69.738
> >
> > Smoothing done, nsteps = 441, tsec = 69.734
> >
> > Smoothing done, nsteps = 441, tsec = 69.806
> >
> > Smoothing done, nsteps = 441, tsec = 70.012
> >
> > Smoothing done, nsteps = 441, tsec = 70.139
> >
> >
> > Killed
> >
> >
> > Any suggestions that may help?
> >
> > Kind regards,
> >
> > Jackie
> >
> >
> >
> >
> > _______________________________________________
> > Freesurfer mailing list
> > Freesurfer@nmr.mgh.harvard.edu
> > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>
> --
> Douglas N. Greve, Ph.D.
> MGH-NMR Center
> gr...@nmr.mgh.harvard.edu
> Phone Number: 617-724-2358
> Fax: 617-726-7422
>
> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
> FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
> www.nmr.mgh.harvard.edu/facility/filedrop/index.html
> Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
>
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-- 
Jacqueline Fitzgerald
PhD Candidate
Department of Psychiatry / Trinity Institute of Neuroscience
Room 3.36b Lloyd Building
Trinity College Dublin
Dublin 2

Tel: (01) 896 4102
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