Dear Doug and experts

I've analyzed structural changes of the subcortical GM by using both VBM
(DARTEL in SPM8) and subcortical volumemetric measurement using FreeSurfer
5.1. While there is no significant volumetric difference between the groups
in VBM (corrected p<0.05), FS results showed that some subcortical GM had
significant volume reductions in patients relative to controls (MANCOVA
controlling for the effect of ICV, age, gender, followed by Bonferroni
correction).
One of the referees raised the question regarding this discrepancy between
the VBM and FS findings.
How can I cope with it?

Thank you in advance for your help.

Kim
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