We have 4 time points for that subject and it's an issue in all 4, to a lesser 
degree in one of them, but still an issue. Same area, same hemisphere, every 
time. Perhaps it is pathology based, I am not entirely sure.



On Jun 28, 2013, at 11:19 AM, Martin Reuter wrote:

> Hi Jonathan,
> 
> is this in cross sectional processing or in longitudinal?
> 
> One thing I notice is significant motion artifacts (ringing), which seem to 
> lead to underestimation of WM, also you could fine tune the skull strip.
> 
> Best, Martin
> 
> On Jun 28, 2013, at 10:19 AM, Jonathan Holt <whats...@umich.edu> wrote:
> 
>> Hi all,
>> 
>> I'm having a bit of trouble with one particular subject for which we brains 
>> for 4-5 different time points. The pial surface is consistently misplaced in 
>> the same area, see attached main/aux volume images. I'm hesitant to manually 
>> replace the white matter myself as I fear it wouldn't be as accurate. 
>> Suggestions on other methods to fix this?
>> 
>> The problem is always in the LH temporal right around the lateral inferior 
>> ventricle and the fusiform and other subcortical structures. 
>> 
>> 
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> ---------------------------------
> Dr. Martin Reuter
> Assistant in Neuroscience - Massachusetts General Hospital
> Instructor in Neurology   - Harvard Medical School
> MGH / HMS / MIT
> 
> A.A.Martinos Center for Biomedical Imaging
> 149 Thirteenth Street, Suite 2301
> Charlestown, MA 02129
> 
> Phone: +1-617-724-5652
> Email: 
>    mreu...@nmr.mgh.harvard.edu
>    reu...@mit.edu
> Web  : http://reuter.mit.edu 
> 
> 
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