Dear Dr Greve,

Together with Dr Hilde Huizenga I am implementing an fMRI study in which we
would like to optimize the design by using Optseq2.  We have a few
questions. Could you please help us out?
Our task consists of 3 runs of 72 trails each, in which participants are
presented with a fixation cross that remains on the screen for a fixed
duration of 1 sec, followed by one out of nine different stimuli that
remains on the screen for a fixed duration of 4 sec.
This gives a scan duration of 360 sec. We would then like to add 25%
jitter, which results in a scan duration of 450 sec, and as TR = 2.0, this
results in 225 time points.

However, Optseq yields an error if ntp is set to 225, ev duration set to
4.0, psdwin dPSD to 1.0 , tnullmin to 1.0 and tnullmax to 6.0
ERROR: could not enforce tNullMax=6 (ntries=100000)
You will need to reduce the number of time points
or increase the number of presentations.

However, reducing the number of time points makes Optseq to only insert
null events of 1.0 or rarely 2.0 sec without much variation. Optimization
with ntp set to 225, ev duration set to 5.0 (=fixed duration of fix +
stimulus), psdwin dPSD to 1.0 , tnullmin to 0.0 (1.0 does not work) and
tnullmax to 6.0 does work. However, this renders Optseq to insert null
events of a fixed duration op 1.0 sec, which is not what we want.

Could you please advise us in how to set these parameters?

Thank you in advance.

Best regards,
Laura Dekkers

-- 
 Laura M.S. Dekkers, MSc
Research assistant
University of Amsterdam - Department of Developmental Psychology
Weesperplein 4
1018 XA Amsterdam - The Netherlands
E-mail: lmsdekk...@gmail.com
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